Sigma-Aldrich Co. LLC

Test & Measurement

Bile Acid Reference Standards aid drug development.

Cerilliant® Snap-N-Spike® solutions include most routinely tested bileÂ- acids and their stable-labeled internal standards. Certified reference materials consist of lithocholic acid, taurocholic acid, and native and deuterium-labeled analogs of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid. Mass spectrometry-based analyses of bile acids...

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Packaging Products & Equipment

Batch Media System aids biopharmaceutical manufacturing.

EX-CELL® Advanced™ products promote performance, streamline regulatory compliance, and offer supply chain security needed in biopharmaceutical environment. As batch media system forÂ- industrial CHO cell lines, EX-CELL Advanced CHO Fed-batch System offers facilitated scale up and adaptation for those in biopharmaceutical development to promote process efficacy. Protein quality...

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Chemicals & Gases

Tryptamine Reference Standards are suited for research, analysis.

Cerilliant® Certified Spiking Solutions® comprise tryptamines intended for use in quantitative mass spec-based testing applications. Specifically, products include solution certified reference materials (CRMs) for 5 synthetic tryptamines — 5-MeO-AMT, 5-MeO-DALT, 5-MeO-MiPT, 5-MeO-DMT, and 5-MeO-DiPT — in addition to 3 naturally occurring tryptamines: N, N-dimethyltryptamine;...

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Controls & Controllers

Sequencing Oligos optimize target sequence assembly.

Manufactured under rigorous conditions toÂ- ensure purity and low levels of cross-contamination, Next-Gen Sequencing Oligos are required for proper assembly of genome sample fragments. With cross-contamination thresholds as low as 0.25% or less, and both ISO 9001 and 13485 manufacturing available, sequencing adapters are suitable for life science research and molecular...

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Architectural & Civil Engineering Products

High-Speed Chromatography Columns use Fused-Core® particle design.

Based on Fused-Core particle design, Ascentis® Express 2.0 micron high-speed ultra high-performance liquid chromatography (UHPLC) columns deliver 300,000 plates/m efficiency. Susceptibility to column plugging is minimized due to 1.0 m frits on column inlet. While columns can be used up to 14,500 psi, design reduces back pressure production and subsequent concerns as well as column...

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Laboratory and Research Supplies and Equipment

Cerilliant Snap-N-Spike® | Snap-N-Shoot® Certified Reference Materials Now Available through Sigma-Aldrich Canada

SAINT LOUIS - Sigma-Aldrich Corporation (NASDAQ: SIAL) is pleased to announce that its Cerilliant® branded products are now available through Sigma-Aldrich Canada. Service through Sigma-Aldrich Canada allows the Company's Canadian customers to readily obtain Cerilliant products domestically, in local currency and language - eliminating the frustrations of customs clearance, import...

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Test & Measurement

Internal Standards come as USDEA-exempt preparations.

Part of Psychoactive Substance Certified Reference Materials line, 9 stable isotope-labeled internal standards of 2C amines are available, including deuterium and 13C labeling. Solutions are suitable for use in isotope dilution methods or other quantitative applications in clinical toxicology, urine drug testing, forensic analysis, or workplace drug screening. Cerilliant Certified Spiking...

Read More »
Laboratory and Research Supplies and Equipment

Corticosteroid Solutions are available as reference materials.

Supplied in concentrations of 100 ug/mL in methanol, Cerilliant® Certified Spiking Solutions® of corticosteroids pregnenolone, 17alpha-hydroxypregnenolone, cortisone, and 11-deoxycorticosterone have stable quantitative format that helps increase efficiency of labor and convenience of use. These solution-based Certified Reference Materials are suitable for preparation of calibrators,...

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Architectural & Civil Engineering Products

UHPLC Columns contain monodisperse sub-2 µm porous silica.

Manufactured using Ecoporous™ silica process, Supelco® Titan UHPLC Columns offer performance greater than 250,000 plates/meter. Uniform particles are packed into rugged column beds that are stable over range of flow and pressure conditions. Columns optimize productivity of pharmaceutical and contract research organizations employing UHPLC for medicinal chemistry, toxicology, and clinical...

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Laboratory and Research Supplies and Equipment

Sigma Life Science Licenses CompoZr Zinc Finger Nuclease Technology to Horizon Discovery

Horizon to utilize both nuclease and rAAV gene editing platforms in custom cell-line generation services and creation of genetically-defined cell line products ST. LOUISÂ-  -- Sigma-Aldrich® Corporation (Nasdaq: SIAL) today announced that Sigma® Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon...

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Company News

MilliporeSigma Inaugurates New, Upgraded Onsite Industrial Water Treatment Plant

- New, state-of-the-art water system treats and reduces concentration of organic solvents BURLINGTON, Mass., Oct. 6, 2020 /PRNewswire/ -- MilliporeSigma today inaugurated a new $14.4 million industrial water treatment plant at its Jaffrey, New Hampshire, location. The upgraded system incorporates advanced technology and complies with town-issued industrial water discharge permits that...

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Test & Measurement

Bile Acid Reference Standards aid drug development.

Cerilliant® Snap-N-Spike® solutions include most routinely tested bileÂ- acids and their stable-labeled internal standards. Certified reference materials consist of lithocholic acid, taurocholic acid, and native and deuterium-labeled analogs of cholic acid, chenodeoxycholic acid, deoxycholic acid, and ursodeoxycholic acid. Mass spectrometry-based analyses of bile acids...

Read More »
Mergers & Acquisitions

Sigma-Aldrich and Merck KGaA, Darmstadt, Germany, Making Progress Toward Completion of Planned Acquisition

ST. LOUIS –Â- Sigma-Aldrich Corporation (NASDAQ: SIAL) announced today it is making progress toward closing the planned acquisition of the Company by Merck KGaA, Darmstadt, Germany. The closing is now expected within the next two months. On August 11, 2015, Sigma-Aldrich and Merck announced they had obtained all necessary antitrust approvals, with the approval of the European Commission...

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Packaging Products & Equipment

Batch Media System aids biopharmaceutical manufacturing.

EX-CELL® Advanced™ products promote performance, streamline regulatory compliance, and offer supply chain security needed in biopharmaceutical environment. As batch media system forÂ- industrial CHO cell lines, EX-CELL Advanced CHO Fed-batch System offers facilitated scale up and adaptation for those in biopharmaceutical development to promote process efficacy. Protein quality...

Read More »
Chemicals & Gases

Tryptamine Reference Standards are suited for research, analysis.

Cerilliant® Certified Spiking Solutions® comprise tryptamines intended for use in quantitative mass spec-based testing applications. Specifically, products include solution certified reference materials (CRMs) for 5 synthetic tryptamines — 5-MeO-AMT, 5-MeO-DALT, 5-MeO-MiPT, 5-MeO-DMT, and 5-MeO-DiPT — in addition to 3 naturally occurring tryptamines: N, N-dimethyltryptamine;...

Read More »
Controls & Controllers

Sequencing Oligos optimize target sequence assembly.

Manufactured under rigorous conditions toÂ- ensure purity and low levels of cross-contamination, Next-Gen Sequencing Oligos are required for proper assembly of genome sample fragments. With cross-contamination thresholds as low as 0.25% or less, and both ISO 9001 and 13485 manufacturing available, sequencing adapters are suitable for life science research and molecular...

Read More »
Architectural & Civil Engineering Products

High-Speed Chromatography Columns use Fused-Core® particle design.

Based on Fused-Core particle design, Ascentis® Express 2.0 micron high-speed ultra high-performance liquid chromatography (UHPLC) columns deliver 300,000 plates/m efficiency. Susceptibility to column plugging is minimized due to 1.0 m frits on column inlet. While columns can be used up to 14,500 psi, design reduces back pressure production and subsequent concerns as well as column...

Read More »
Laboratory and Research Supplies and Equipment

Cerilliant Snap-N-Spike® | Snap-N-Shoot® Certified Reference Materials Now Available through Sigma-Aldrich Canada

SAINT LOUIS - Sigma-Aldrich Corporation (NASDAQ: SIAL) is pleased to announce that its Cerilliant® branded products are now available through Sigma-Aldrich Canada. Service through Sigma-Aldrich Canada allows the Company's Canadian customers to readily obtain Cerilliant products domestically, in local currency and language - eliminating the frustrations of customs clearance, import...

Read More »
Test & Measurement

Internal Standards come as USDEA-exempt preparations.

Part of Psychoactive Substance Certified Reference Materials line, 9 stable isotope-labeled internal standards of 2C amines are available, including deuterium and 13C labeling. Solutions are suitable for use in isotope dilution methods or other quantitative applications in clinical toxicology, urine drug testing, forensic analysis, or workplace drug screening. Cerilliant Certified Spiking...

Read More »
Laboratory and Research Supplies and Equipment

Corticosteroid Solutions are available as reference materials.

Supplied in concentrations of 100 ug/mL in methanol, Cerilliant® Certified Spiking Solutions® of corticosteroids pregnenolone, 17alpha-hydroxypregnenolone, cortisone, and 11-deoxycorticosterone have stable quantitative format that helps increase efficiency of labor and convenience of use. These solution-based Certified Reference Materials are suitable for preparation of calibrators,...

Read More »

All Topics

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