Kit enables whole genome amplification.

Press Release Summary:



GenomePlex® Tissue Whole Genome Amplification Kit includes all reagents needed for extraction and whole genome amplification from as little as 0.1 mg of fresh, frozen, or formalin-fixed paraffin-embedded tissue. It incorporates optimized tissue lysis and extraction procedure, which eliminates need for deparaffinization or DNA purification. Applications include QPCR, microsatellite analysis, SNP analysis, Comparative Genomic Hybridization, microarrays, and other genotyping analysis.



Original Press Release:



Sigma-Aldrich Launches GenomePlex® Tissue Whole Genome Amplification Kit



ST. LOUIS, Jan. 23 - Sigma-Aldrich (NASDAQ:SIAL), a leading $1.7 billion Life Science and High Technology company, is pleased to launch the GenomePlex Tissue Whole Genome Amplification (WGA) Kit. This kit is the latest addition to the GenomePlex product line and includes all of the reagents needed for extraction and whole genome amplification from as little as 0.1 mg of fresh, frozen or formalin-fixed paraffin-embedded (FFPE) tissue.

"We are very excited about the capabilities of the GenomePlex Tissue WGA kit to provide customers with a best-in-class product for DNA amplification of damaged and degraded material such as FFPE tissues," said Keith Jolliff, Director of Strategic Marketing at Sigma-Aldrich. "These samples hold a wealth of information for the study of many diseases such as cancer."

The new GenomePlex Tissue WGA kit incorporates an optimized tissue lysis and extraction procedure, which eliminates the need for deparaffinization or DNA purification. The WGA product can be used in numerous downstream applications, including QPCR, microsatellite analysis, SNP analysis, Comparative Genomic Hybridization (CGH), microarrays, and other genotyping analysis. Amplification results in microgram quantities of DNA.

The GenomePlex Tissue Whole Genome Amplification Kit is derived from the proprietary amplification method that is based upon random fragmentation of the genome and conversion of the resulting small fragments to PCR-amplifiable OmniPlex library molecules flanked by universal priming sites. The OmniPlex® library is then PCR amplified using universal oligonucleotide primers and a limited number of cycles.

About Sigma-Aldrich:
Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, and pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 35 countries and has 7,300 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at sigma-aldrich.com.

CONTACT:
Sean Battles
Sigma-Aldrich
+1-314-286-7616
sean.battles@sial.com

Web site: http://www.sigma-aldrich.com/

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