Phosphopeptide Enrichment Kit comes with necessary controls.

Press Release Summary:



Using technology based on Ga+3 chelate on silica, PhosphoProfile(TM) I offers proteomics researchers advantages such as low non-specific binding, no bias in selectivity of phosphorylation state, maximum sensitivity, and accelerated sample handling. Phosphoproteins are digested with included Proteomics Grade Trypsin, resulting in phosphopeptides captured in spin-tubes. Up to 25 nanomoles of phosphopeptide can be captured and recovered from complex samples.



Original Press Release:



Sigma-Aldrich Launches New PhosphoProfile(TM) I Phosphopeptide Enrichment Kit



ST. LOUIS, Sept. 11 -- Sigma-Aldrich Research Biotech, a division of Sigma-Aldrich (NASDAQ:SIAL), has launched the PhosphoProfile(TM) I Phosphopeptide Enrichment Kit, a new kit for the enrichment of phosphopeptides.

"This launch of the new phosphopeptide enrichment kit demonstrates Sigma-Aldrich's commitment to develop and offer cutting-edge proteomic technologies," said George Lipscomb, Product Manager, Proteomics, for Sigma-Aldrich's Research Biotech division. "We are proud to further enable the discovery and success of researchers through innovative technologies and service."

The technology is based on a novel Ga+3 chelate on silica that provides a robust method for phosphoproteomics. This new approach offers several advantages to proteomics researchers, including very low non-specific binding, no bias in selectivity of phosphorylation state, high sensitivity, and fast sample handling, especially for small precious samples. Phosphoproteins are digested with the included Proteomics Grade Trypsin, resulting in high-quality phosphopeptides that are captured in the convenient spin-tubes. Recovered phosphopeptides are then ready for analysis by either MALDI-TOF or ESI mass spectrometry. Up to 25 nanomoles of phosphopeptide can be captured and recovered from complex samples. Also included are the necessary buffers and mono and tetra phosphopeptide controls commonly used to verify performance eliminating the requirement of additional purchases and risk of data misinterpretation.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 35 countries and has 7,200 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award- winning Web site at sigma-aldrich.com/ .

CONTACT: Sean Battles of Sigma-Aldrich, +1-314-286-7616, or sean.battles@sial.com

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