Thermo Fisher Scientific Nano-UHPLC System Significantly Increases Productivity During Proteomics Research at the University of Southern Denmark
ODENSE, Denmark - Thermo Fisher Scientific Inc. the world leader in serving science, today announced that the Center for Experimental Bioinformatics (CEBI) at the University of Southern Denmark is using Thermo Scientific nano-ultra high performance liquid chromatography (UHPLC) technology to accelerate productivity and improve efficiencies during its proteomics research. Implementation of the Thermo Scientific EASY-nLC 1000 has enabled 34 percent more peptide and 22 percent more protein identifications within the CEBI laboratory, significantly increasing productivity. Additionally, the instrument has improved separations and facilitated the analysis of more complex samples within the laboratory.
Based in Odense, the University of Southern Denmark's Department of Biochemistry and Molecular Biology is world-renowned in the field of proteomics, with research focusing on gene structure and organization, regulation and RNA translation. CEBI is a specialist proteomics research laboratory, aimed at applying modern methods of mass spectrometry and proteomics to functional analysis of genes.
Prior to implementing nano-UHPLC technology, CEBI used conventional HPLC. However they needed a more complete solution, such as EASY-nLC 1000, to accelerate productivity and improve efficiencies. The EASY-nLC 1000 is used in conjunction with Thermo Scientific ion trap and Orbitrap mass spectrometers for a wide range of proteomics research, including the study of complex mouse dendritic cells.
Using the EASY-nLC 1000 has allowed CEBI to take advantage of the unique ability to facilitate dedicated separation of biomolecules at ultra-high pressures. The higher operating pressures provided by the EASY-nLC 1000 have increased the number of peptide and protein identifications performed within the laboratory by 34 percent and 22 percent respectively. The instrument also allows selection of the most appropriate column dimensions and solid phase materials in order to identify the most suitable configuration to match analytical requirements. Using thinner, longer columns and smaller beads has improved separation and ionization, enhancing sensitivity and allowing the CEBI team to scale down experiments and reduce costs.
"The EASY-nLC 1000 is a highly robust instrument offering nano-UHPLC performance dedicated to proteomics scientists," said Lasse Falkenby, research assistant at CEBI. "We decided to implement the new system in our laboratory as we felt that it would revolutionize the way we perform LC-MS analyses. The instrument has allowed our laboratory to increase productivity considerably in a way that would never have been possible before. Implementation was a very smooth process requiring minimal configuration effort and the Thermo Fisher Scientific team of experts provided valuable support both throughout and after this process."
For more information on the Thermo Scientific EASY-nLC 1000, please visit www.thermoscientific.com/easylc, call (781) 933-4689 or e-mail analyze@thermofisher.com.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of nearly $11 billion, we have approximately 37,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com
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