Thermal Product Solutions Ships Two Gruenberg Depyrogenation Sterilizers to Pharmaceutical Industry

Thermal Product Solutions, a global manufacturer of thermal-processing equipment, announced the shipment of two (2) Gruenberg Depyrogenation Sterilizers to the Pharmaceutical Industry. The units will be used for sterilizing pharmaceutical equipment.

These pharmaceutical sterilizers have maximum temperature ratings of 280°C with work chamber dimensions of 36” W x 36” D x 53” H. The Gruenberg sterilizers were constructed from a structural steel frame that supported the 304L stainless steel interior chamber liner and the 304 #4 polished stainless-steel exterior. All interconnecting struts are non-continuous which keeps the exterior cool. 

Located in a plenum chamber in the top of the sterilizers, circulation blowers direct air through circulation ducts located on one side of the workspace. The air passes through high temperature HEPA filters first, and then enters the chamber through a semi-pierced duct wall. The air flows horizontally across the product, exits through a semi-pierced duct wall on the opposite side, and enters a recirculation duct. The air is then directed back to the blower for reheating and recirculation.

Rapid ramp HEPA filters on the circulation and exhaust air flow systems were added to allow the machines to ramp up to temperature and cool down at a rate of 5°C per minute. An Allen Bradley touchscreen HMI with PLC were installed on each unit for temperature and process control. The system was also supplied with an array of thermocouples to monitor the product inside of the chamber.

“These single door sterilizers were designed and tested to provide ISO 5 or Class 100 sterilizing conditions at ambient and operating temperatures.

– Jonathan Young, Gruenberg Product Manager

Unique features of these Gruenberg Depyrogenation Sterilizers include:

  • Stainless steel 304 with a #4 finish exterior
  • Fully welded 304L stainless steel interior liner
  • Removable floor stand
  • 4 inches of insulation
  • ¾” radius corners
  • Pneumatic door locks
  • Air intake HEPA filter
  • Air exhaust HEPA filter
  • Circulation HEPA filter
  • Accelerated ramp feature
  • +/-5°C at 232°C temperature uniformity
  • NEMA 12 control console
  • Allen Bradley PLC and HMI
  • High limit thermostat
  • Fused main power disconnect switch
  • Yokogawa strip chart recorder
  • Monitoring thermocouples inside chamber
  • Tested for ISO 5 conditions

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