New Probe Provides a Major Sensitivity Enhancement in Raman Spectroscopy

IRVINE, Calif., Feb. 25, 2007 - Axiom Analytical Inc., a leading supplier of sampling equipment, software, and integrated systems for all forms of vibrational spectroscopy, today announced the introduction of its RFP-460 Multipass Raman Probe. This probe provides up to an order of magnitude enhancement in the sensitivity of Raman spectroscopy when used for the analysis of gases and clear liquids. The principles underlying its operation were described recently in a paper given by Dr. W. Michael Doyle at the International Forum on Process Analytical Chemistry (IFPAC), held in Baltimore Md., January 27 - 30, 2008 ( The paper reported the achievement of marked sensitivity enhancement, with no undesirable side effects, through the use of a design previously developed by Dr. Doyle (US Patent 6,795,177 B2). The significantly improved performance was made possible by combining the multipass approach with recent advances in interference filter technology.

Raman spectroscopy is a powerful technique for chemical analysis which combines the specificity of mid-infrared spectroscopy with the convenience and flexibility of near-infrared. It is based on the use of a focused laser beam to cause a condensed substance to emit a spectrum of optical radiation that is uniquely related to its molecular structure. Dr. Doyle's advance takes advantage of the fact that Raman scattering is an extremely week phenomenon and is only made practical by the high energy density of the focused laser beam. Very little attenuation of the laser signal takes place. In principle, it is thus possible to pass the same laser beam through a sample more than once. Dr. Doyle's approach makes it possible to accomplish this by means of a straight forward modification to Axiom's standard Raman probes -- making multi-pass Raman practical, economical, and highly effective.

Pittcon 2008

The RFP-460 Multipass Raman Probe will be exhibited at Axiom's booth (#4323) at the upcoming Pittcon Conference in New Orleans.

About Axiom Analytical, Inc

Axiom Analytical, Inc. was founded in 1988 by Dr. Mike Doyle and Norm Jennings, pioneers in the field of process FTIR spectroscopy. The Company's mission is to develop and market the robust sampling equipment, software, and integrated systems required to fully realize the potential of molecular spectroscopy for solving economically significant problems both in laboratory analysis and manufacturing processes. The Company's products are employed in diverse industries ranging from basic chemicals to pharmaceuticals, semiconductors, and polymer processing.

More information about Axiom Analytical Inc. can be found at

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