Insulet's Tubeless, Wireless Insulin Pump Features TOPAS® Cyclic Olefin Copolymer

Insert Molded Plunger Delivers Drug Compatibility and Dimensional Stability in Breakthrough Device for Diabetes Treatment

FLORENCE, Ky. – The industry's first tubeless and wireless insulin pump, recently upgraded by developer Insulet Corp., Bedford, Mass., features an insert molded Plunger made of TOPAS® cyclic olefin copolymer (COC) from TOPAS Advanced Polymers. The next-generation OmniPod® Insulin Management System offers people living with insulin-requiring diabetes all the benefits of insulin pump therapy, while at the same time providing freedom and ease of use, and overall quality of life improvements.

The newly released OmniPod is 34% smaller and 25% lighter than the original model, and received 510(k) clearance from the U.S. Food & Drug Administration (FDA) in December 2012. TOPAS COC, which provides purity, drug compatibility, biocompatibility, and dimensional stability, has been used in this critical high-performance Plunger since the first-generation device was commercialized in late 2005.

The OmniPod Insulin Management System consists of the OmniPod which holds and delivers the insulin and the PDM (Personal Diabetes Manager) which communicates wirelessly with the OmniPod to program insulin delivery. The OmniPod includes a two-component insert molded Plunger which consists of a stainless steel Lead-screw and Fill Rod which are insert molded with TOPAS COC resin. The two-component Plunger has an elliptical shape and measures approximately 3/8-in (9.5 mm) by 5/8-in (15.9 mm).

TOPAS COC provides strong dimensional stability since the Plunger moves just 0.000156-in (0.004 mm) per increment of insulin delivery. The dimensions of the Plunger and Lead-screw are critical because small amounts of insulin have a significant effect on blood sugar levels. The OmniPod attaches directly to the body and is usable for up to three days of basal-bolus insulin therapy – delivering boluses of insulin after meals and in steady rates throughout the day. The OmniPod holds 200 units of rapid-acting insulin, which Insulet says meets the needs of most Type 1 diabetes patients' three-day insulin requirements.

The material's stability helps successfully manage the Plunger and Reservoir interface which is critical to the function of the device and provides adequate compression to maintain seal integrity, according to Kevin Schmid, Insulet's Vice President of Business Development and Advanced Technology.

"TOPAS COC fills an important role in the drive system of the OmniPod Insulin Management System," said Schmid. "It's a well-respected material because of its drug compatibility and other high-performance attributes."

Unlike other engineering thermoplastics or glass, TOPAS COC offers a non-ionic, minimally reactive surface. This non-polar substrate does not promote adsorption, denaturation, aggregation, or precipitation. With lower leachables and extractables, glass-clear TOPAS resin preserves long-term drug purity enabling better quality at high yields.

About Insulet Corp.

Insulet Corporation (NASDAQ: PODD) is an innovative medical device company dedicated to making the lives of people with diabetes easier. Through its OmniPod Insulin Management System, Insulet seeks to expand the use of insulin pump therapy among people with insulin-dependent diabetes. The OmniPod is a revolutionary and easy-to-use tubeless insulin pump that features just two parts and fully-automated cannula insertion. Insulet's subsidiary, Neighborhood Diabetes, is a leading distributor for diabetes products and supplies, delivered through a high touch customer service model. To read inspiring stories of people with diabetes living their lives to the fullest with OmniPod, visit our customer blog, Suite D:

Founded in 2000, Insulet Corporation is based in Bedford, Mass. For more information, visit:

About TOPAS Advanced Polymers 

TOPAS Advanced Polymers manufactures and markets TOPAS cyclic olefin copolymers (COC) for advanced packaging, healthcare, optical, and other applications worldwide. It also supplies the chemical intermediate norbornene. The company is a joint venture of Daicel Corporation and Polyplastics, both of Japan. Headquartered in Frankfurt, Germany, it has a U.S. subsidiary in Florence, Ky., and operates the world's largest COC plant in Oberhausen, Germany. For more information, visit

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Joseph Grande    


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