BOC Sciences has devoted a lot of effort in reorganizing its inhibitor products and make them an individual branch of the inhibitors they provide. Then 19th, August, the company officially announced that they began to provide immune checkpoint inhibitors from then on.
With the potential of immune therapies getting more discovered, they are more widely tried for various diseases. From immune diseases to cancers, they showed great power in alleviating the conditions. Recent studies have made breakthroughs in the application of immune therapies on lung cancer, and it turned out that the treatment is especially helpful for non small cells lung cancer, and some of the treatments have entered the stage of clinic trial after the approval of Food and Drug Administration of America (FDA).
Immune checkpoints are proteins that are responsible for turning on or off the immune signals to hindering the T-cells from killing cancer cells. Immune checkpoint inhibitors suggested as its names are the compounds that work to inhibit the activities of such proteins and keep the T-cells killing cancer cells continuously.
With the success of ipilimumab in 2011, the therapy is found beneficial also to many other types of cancers based on the same theory, then deeper studies were carried out. As a result, immune checkpoint inhibitors targeting the proteins on T-cells or cancer cells are developed. At BOC Sciences, about 25 small branches of immune checkpoint inhibitors are available, including IDO1, TDO and so on. And in total about 200 hundred inhibitors are covered. The variety will be expanded with new scientific studies and market needs.
In the first batch, PD-1 and PD-L1 are among the featured products in this line. What is apparently different from other chemicals listed on the site is that, all inhibitors in this category are attached with detailed description on their pharmaceutical or chemical characters, and some of them are provided with paper reference where the inhibitors are involved.
Along with the launch of immune checkpoint inhibitors, the company also released Hsp90 inhibitors, another important branch of inhibitor product for present scientific researches.
BOC Sciences is a comprehensive chemical supplier in USA. With more than 11 years in the field, the company is capable of providing chemicals in good quality. Besides with inhibitors, natural compounds, GMPs, APIs, chiral molecules, stem cells molecules and so on are also available there. The company is working on to expand the variety of immune checkpoint inhibitors, as well as rich the information attached to the chemicals.