SPE Formats assist bioanalytical sample preparation.

Press Release Summary:



OMIX® micro extraction solid phase extraction formats for bioanalytical research feature monolithic sorbent technology that allows for extractions with low elution volumes. OMIX micro extraction pipette tips enable vacuum-free SPE processing of biofluid samples directly in pipette tips. OMIX 96-well plate is designed to process small sample volumes in SBS-compatible device which interfaces with standard 96-well liquid-handling equipment.



Original Press Release:



Varian, Inc. Introduces Two Revolutionary New OMIX SPE Formats for Bioanalytical Sample Preparation



PALO ALTO, Calif., Jan. 18 / -- Varian, Inc. (NASDAQ: VARI) today introduced two new OMIX® micro extraction solid phase extraction (SPE) formats for bioanalytical research that deliver improved performance and a faster, more streamlined sample preparation process. The first enables vacuum-free SPE processing of biofluid samples directly in the tip of a popular liquid-handling device. The second is a new micro-volume 96-well plate specifically designed to process small sample volumes.

Pharmaceutical and biopharma researchers are under tremendous pressure to accelerate new drug discovery and development. OMIX features a unique monolithic sorbent technology that allows for highly efficient extractions performed with low elution volumes, improving sample throughput and analytical quality.

The first new format, OMIX micro extraction pipette tips for TOMTEC®'s Quadra instruments, eliminates the need for vacuum processing and allows TOMTEC's instruments to be used in a fully automated, walk-away capacity. For the first time SPE can be performed directly in the Quadra compatible pipette tips. This is possible only due to the bi-directional, clog-free flow properties of the OMIX monolithic media. As a result, sample clean-up is simplified and reproducibility is improved.

A second new format, OMIX 96-well plates, features the same small-bed micro processing capabilities in an SBS-compatible device which interfaces with standard 96-well liquid-handling equipment used in bioanalytical research. Analysts can reduce their elution volumes by a factor of up to 10 and still maintain equal or superior recoveries and reproducibility. This improvement offers significant throughput gains because direct injection of the small extracts achieved with OMIX eliminates the need for additional transfer and evaporation steps.

Sample preparation is crucial to scientists focusing on bioanalytical and pharmaceutical research because they must remove salts, proteins, lipids, and other endogenous sample components prior to analysis with LC/MS/MS (liquid chromatography/mass spectrometry/mass spectroscopy). Additionally, pharmaceutical researchers work with limited sample volumes so micro-volume purification devices are critical to improving sensitivity and achieving more reliable quantification of drugs and metabolites.

"The expansion of our OMIX tips for pharmaceutical applications further delivers on our strategy to focus on consumable products in the high-growth life sciences area," said Stephen Schultheis, Consumable Products Vice President and General Manager, Varian, Inc.

Varian, Inc. supplies a broad range of scientific instruments and laboratory consumable supplies for health science applications. As part of its strategy, the company maintains a balanced approach to enhancing and expanding its products for life science and industrial customers.

Varian, Inc. is a leading worldwide supplier of scientific instruments and vacuum technologies for life science and industrial applications. The company provides complete solutions, including instruments, vacuum components, laboratory consumable supplies, software, training, and support through its global distribution and support systems. Varian, Inc. employs approximately 3,700 people and operates manufacturing facilities in 13 locations in North America, Europe, and the Pacific Rim. Varian, Inc. had fiscal year 2005 sales of $773 million (excluding the divested Electronics Manufacturing segment), and its common stock is traded on Nasdaq under the symbol, "VARI." Further information is available on the company's Web site: www.varianinc.com

For More Information, Contact:
Lauren Lum
Varian, Inc.
650-424-5286
lauren.lum@varianinc.com

Source: Varian, Inc.

Web site: www.varianinc.com/

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