Refractive Index Detector is designed for UHPLC systems.

Press Release Summary:

Intended for use with UHPLC systems using columns packed with small beads, Optilab UT-rEX (UHPLC refractometer with EXtended range) uses miniaturized components and semiconductor photodiode technology as well as proprietary computer algorithms. Linearity over concentration range and sensitivity to samples that are not UV active make detector suited for UHPLC. Dead volume is <1.5 µL, there are no range or gain settings, and temperature control can be programmed from 4 to 50°C.

Original Press Release:

First Refractive Index Detector for UHPLC

Santa Barbara, CA -- Wyatt Technology announces the immediate availability of the Optilab UT-rEX (UHPLC refractometer with EXtended range), the first RI detector specifically designed for use with UHPLC systems using columns packed with small beads.

Using a combination of miniaturized components and cutting-edge semiconductor photodiode technology as well as proprietary computer algorithms, the UT-rEX presents a host of instrument firsts:

Besides UV, mass spectrometry and evaporative light scattering, there has been no RI detector available for UHPLC applications until now. The linearity of the UT-rEX over a wide concentration range coupled with its sensitivity to samples that are not UV active, make it an exciting addition to UHPLC.

Due to the extremely small volumes of UHPLC, the dead volume from the UT-rEX is <1.5 µL as compared to 10-20 µL or more from other RI detectors. As a result, the superior resolution from UHPLC columns and instruments will not be compromised with the UT-rEX RI detector.

In addition, there are no range or gain settings. The full range of instrument detection is always present, and the full sensitivity exists over the entire range. The small flow cell and proprietary temperature regulation enable stable RI baselines and RI signals which further enhance the detector’s sensitivity.

The new Optilab UT-rEX can be operated below ambient temperatures as easily as above ambient. No hassle temperature control can be programmed down to 4°C or as high as 50°C. The Optilab UT-rEX is ompatible with all UHPLC systems.

To learn more about Wyatt Technology’s Optilab UT-rEX and its capabilities, please visit or email

About Wyatt

Based in Santa Barbara, California, Wyatt Technology is the world’s leading provider of instruments for absolute macromolecular characterization. With over 40 years’ experience developing multi-angle light scattering detectors, working with customers in the biotechnology, chemical, petrochemical, pharmaceutical, academic and government arenas, Wyatt prides itself on its entrepreneurial spirit, and the uniqueness of its offerings. The Company’s groundbreaking technology and uncompromising levels of customer care make Wyatt the global hallmark in its field. For more information, please visit

For further press information please contact:

Gemma Clulow

The Scott Partnership

 1 Whiteside

Station Road

 Holmes Chapel



United Kingdom

Tel: + 44 1477 539539 

Fax: +44  1477 539540  


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