Protein Characterization Takes Centre Stage in Malvern's Analytica Exhibits


Malvern, UK: At Analytica 2010 (23-26 March 2010, Munich, Germany) Malvern Instruments will focus on its range of analytical instrumentation for life science applications, with an emphasis on the company's comprehensive solutions for characterizing proteins and other macromolecules. Today Malvern offers a variety of options, with a range of systems that can be configured to meet the analysis requirements of individual laboratories. These include the Zetasizer family, which employs dynamic and static light scattering to measure size and molecular weight, and the full range of Viscotek advanced gel permeation / size exclusion chromatography (GPC/SEC) systems and detectors for rapid, reliable characterization of both molecular weight and molecular structure.

In addition to the established and widely used Zetasizer Nano system, Malvern's Zetasizer family now includes a system dedicated to the analysis of proteins and other biomolecules. Designed and optimised for maximum sensitivity and minimum sample volume, the Zetasizer Micro V is a dedicated system that supports improved understanding and management of a wide range of biomolecule applications. These include: optimising sample and storage conditions; verifying the quaternary structure of protein complexes; identifying thermal characteristics; and assessing protein solubility and sample purity.

When it comes to GPC/SEC, Malvern provides a wide choice for chemists seeking either a complete system or an additional detector to enhance an existing set-up. At the heart of the company's chromatography range are Viscotek advanced GPC/SEC systems. These include the powerful yet easy to use TDAmax, which can be configured with up to four detectors to deliver maximum information from a single experiment. Light scattering, viscosity, concentration, refractive index and UV detection are all available on the TDAmax. The system delivers information on absolute molecular weight without correction or extrapolation, oligomeric composition and aggregation, protein size and density, conjugate composition and second virial coefficient. OmniSEC software not only offers standard methodologies for instrument control, analysis and customised reporting, it can also deal with specialised applications, such as the analysis of pegylated proteins.

Malvern application experts are always available to help configure systems for specific measurement needs, and will be pleased to discuss individual requirements with visitors to the Malvern stand A1.320 at Analytica. www.malvern.com/analytica2010

About Malvern Instruments

Malvern Instruments provides a range of complementary materials characterization tools that deliver inter-related measurements reflecting the complexities of particulates and disperse systems, nanomaterials and macromolecules. Analytical instruments from Malvern are used in the characterization of a wide variety of materials, from industrial bulk powders to nanomaterials and delicate macromolecules. A broad portfolio of innovative technologies is combined with intelligent, user-friendly software. These systems deliver industrially relevant data enabling our customers to make the connection between micro (such as particle size) and macro (bulk) material properties (rheology) and chemical composition (chemical imaging).

Particle size, particle shape, zeta potential, molecular weight, chemical composition and rheological properties measurements are now joined by advanced chromatography solutions (GPC/SEC), extending Malvern's technologies for protein molecular weight, size and aggregation measurements, and synthetic polymer molecular weight and distribution. The company's laboratory, at-line, on-line and in-line solutions are proven in sectors as diverse as cement production and pharmaceutical drug discovery.

Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Korea and Japan, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com

For press information, please contact:
Trish Appleton,
Kapler Communications
Knowledge Centre, Wyboston Lakes, Great North Road,
Wyboston, Bedfordshire,
MK44 3BY, UK
Tel: +44 (0)1480 479280;
Fax: +44 (0)1480 470343
trish@kapleronline.com

USA contact:
Marisa Fraser,
Malvern Instruments Inc.
117 Flanders Road,
Westborough, MA 01581-1042 USA
Tel: +1 508 768 6400
Fax: +1 508 768 6403
marisa.fraser@malvern.com

Please send sales enquiries to:
Alison Vines,
Malvern Instruments Ltd
Enigma Business Park, Grovewood Road,
Malvern, Worcestershire WR14 1XZ UK
Tel: +44 (0) 1684 892456;
Fax: +44 (0) 1684 892789
salesinfo@malvern.com

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