Oxidation Assay is optimized for quickness and sensitivity.
Press Release Summary:
Designed to help researchers understand mechanism of cellular aging, OxyELISA(TM) Oxidized Protein Quantitation kit provides all reagents necessary for quantitative, high-throughput detection of modified proteins in cells undergoing oxidative stress. Solution detects carbonyl groups introduced into cells by oxygen free radicals and other reactive species. It uses direct labeled monoclonal antibody that is readily detected without secondary antibody.
Original Press Release:
New OxyELISA(TM) Kit Provides Quantitative Measure of Oxidative Stress
High throughput kit improves specificity and shortens assay time
Billerica, Massachusetts-July 29, 2008-Millipore Corporation, a Life Science leader providing technologies, tools and services for bioscience research and biopharmaceutical manufacturing, today announced the launch of its OxyELISA Oxidized Protein Quantitation kit, providing all reagents necessary for quantitative, high throughput detection of modified proteins in cells undergoing oxidative stress.
Oxidative stress is a cellular condition particularly relevant to aging and age-related diseases, such as Alzheimer's disease, Parkinson's disease, and dementia. The OxyELISA kit, by providing a fast and sensitive assay for oxidation, can help researchers, especially neuroscientists, to understand the mechanism of cellular aging.
As result of oxidative stress, oxygen free radicals and other reactive species introduce carbonyl groups into proteins in the cell. The OxyELISA kit detects these carbonyl groups, which are hallmarks of the cellular oxidative stress level. The kit uses a direct labeled monoclonal antibody that is readily detected without a secondary antibody, making the ELISA assay more specific, easier to use, and faster.
OxyELISA users can count on full technical support from Millipore, complemented by a comprehensive offering of reagents and assays for analyzing oxidative stress. Researchers can investigate superoxide dismutase activity, tyrosine nitrosylation, oxidized glutathione, and more. The OxyELISA kit complements Millipore's more qualitative OxyBLOT(TM) assay, which detects oxidation of individual proteins after separation on a gel.
Millipore has evolved from a high-performance filtration products and services company into a leading provider of tools and services and a key partner of choice for Life Science customers. We've transformed ourselves through R&D investment, organic growth, and acquisitions such as Chemicon, Upstate, Linco, Celliance, Newport Bio Systems, NovAseptic AB and MicroSafe. The integrated Millipore offers more innovative technologies and stronger applications support to streamline processes and provide consistently reliable results. The expert scientists in our Life Sciences business unit understand the complexity of Life Science research and can work with researchers around the world to resolve their most difficult challenges in cell biology, stem cell biology, protein research, and cell signaling applications.
About Millipore
Millipore (NYSE: MIL) is a Life Science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world's challenging human health issues. From research to development to production, our scientific expertise and innovative solutions help customers tackle their most complex problems and achieve their goals. Millipore Corporation is an S&P 500 company with 6,000 employees in 47 countries worldwide. For more information, please contact Millipore Tech Service at 1-800-548-7853 or 951-676-8080 or visit www.millipore.com.
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