Non-Invasive Analyzer examines O2 in pharmaceutical blisters.

Press Release Summary:

With optical sensor that gives off light directly related to amount of oxygen present, OpTech® - O2 system enables non-invasive, non-destructive thermoformed blister package testing. System complies with ASTM F2714, is stable in ambient light, and can determine oxygen headspace, dissolved oxygen, ingress, and permeation rate in flexible and rigid packaging under real-life conditions. Values are read in 0.5 sec, and oxygen measurement range is 0.001%-25%.

Original Press Release:

Mocon Launches Non-Invasive Oxygen Analyzer Capability for Headspace Gas Testing of Pharmaceutical Blisters

Minneapolis, MN - MOCON, Inc. (NASDAQ: MOCO), the world's leading manufacturer of permeation instrumentation, is announcing new capability for its OpTech® - O2 system.

Non-invasive, non-destructive thermoformed blister package testing is now possible due to the development of an optical sensor that will "fluoresce" or give off light directly related to the amount of oxygen present. OpTech® - O2 technology is ideal for determining oxygen headspace and ingress in flexible and rigid packaging.

"Some blister packaging applications depend on gas flushing to enhance the product's shelf life. However, modified atmosphere can be compromised by poor packaging seals, material breakdown, weak barrier properties, pinholes, etc. This is why using a precise and sensitive package performance test method is so important-especially for drug packaging," said Ed Emerson, manager, healthcare business development, MOCON.

Until now, blister testing alternatives either involved invasive testing or complicated off-line procedures. Other blister testing procedures are labor intensive, or without the degree of accuracy that the OpTech® - O2 system provides.

"This breakthrough technology will have a dramatic impact on how pharmaceutical companies conduct oxygen analysis," explained Emerson. "The OpTech® - O2 system offers a simple method to quickly evaluate what is happening inside a closed blister package under real-life conditions."

MOCON is a leading provider of instrumentation and consulting and laboratory services to medical, pharmaceutical, food and other industries worldwide. See for more information.

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