New Human Cell Culture Medium Can Support Cell Growth and Viability

Press Release Summary:

  • Mimics the metabolic profile of human plasma
  • Designed to provide researchers with a realistic view of cell growth within the human body
  • Contains salt concentrations found in human plasma, and concentrations of over 60 polar metabolites

Original Press Release:

Thermo Fisher Scientific Announces New Human Plasma-Like Cell Culture Medium

First-of-its-kind medium resembles the natural cellular environment found in the human body for more physiologically relevant cell culture models

CARLSBAD, Calif., March 22, 2021 /PRNewswire/ -- Thermo Fisher Scientific today launched the new Gibco Human Plasma-like Medium (HPLM), the first cell culture medium on the market that mimics the metabolic profile of human plasma that is designed to provide researchers with a realistic view of cell growth within the human body.

Gibco HPLM contains the same salt concentrations found in human plasma, as well as the same concentrations of over 60 polar metabolites, such as amino acids, nucleic acids, sugars and small organic acids. By resembling the natural cellular environment found in the body, HPLM provides researchers the ability to study the impact of physiologically relevant cell media on their specific research applications, including cancer and other diseases. When supplemented with fetal bovine serum (FBS), HPLM can support cell growth and viability that are comparable to that of conventional basal media formulations supplemented with FBS. For most cell lines, adaptation is not required to transition from conventional medium to HPLM.

"Innovative technology such as the Gibco Human Plasma-Like Medium is testament to the incredible work being led by Thermo Fisher's research partners," said Amy Butler, president of biosciences, Thermo Fisher Scientific. "Collaboration between industry and academia is vital to the pursuit of innovation and development of fit-for-purpose materials that improve scientists' understanding of human disease and strategies to address them."

Human Plasma-like Medium was invented by Jason R. Cantor of the Morgridge Institute for Research in Madison, Wisconsin and David M. Sabatini of the Whitehead Institute at the Massachusetts Institute of Technology in Cambridge, Mass. Drs. Cantor and Sabatini are inventors on a patent application for HPLM assigned to Whitehead Institute.

For more information on the Gibco Human Plasma-like Media, please visit

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $30 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. Our global team of more than 80,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon. For more information, please visit

Media Contact Information:
Mauricio Minotta
Phone: 760-805-5266

Olivia Hayum
Phone: 978-201-9131

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