New DNA Modifying Enzyme Available with Vaccinia Capping Enzyme and T4 DNA Ligase

Press Release Summary:

  • Improves the stability and translation ability in vitro transcribed RNA for transfection and microinjection
  • Repairs single-strand nicks in duplex DNA, RNA or DNA/RNA hybrids
  • Ideal for cut, edit, unfold, ligate or remove nucleic acid fragments

Original Press Release:

Creative Enzymes Introduces DNA Modifying Enzymes for Molecular Biology Research

Creative Enzymes, an excellent supplier and manufacturer located in New York, is always hammering away at research and trials in order to provide customers with as many enzyme services and products as possible. DNA modifying enzymes play an important role in molecular biology research. With the aim of developing efficient enzyme tools to better support your research, Creative Enzymes is pleased to announce some of the best and most affordable DNA modifying enzymes on the market.

Modern molecular biology is enabled by the use of DNA-modifying enzymes whose function is to cut, edit, unfold, ligate or remove nucleic acid fragments. These molecular tools support a variety of molecular applications, including cloning, mutagenesis, and DNA and RNA purification, including multiple enzyme types. These include DNA or RNA ligases, which join two separate DNA and RNA molecules, respectively. Various recombinases enable site-specific incorporation of sequences to form recombinant DNA constructs. Polynucleotide kinases can add phosphate groups or label DNA and RNA. Nucleases, including DNases and RNases, cleave or degrade nucleic acids for applications such as purification or analysis.

Here are some featured DNA modifying enzymes products you may be interested in:

1. Vaccinia Capping Enzyme

The vaccinia virus capping system uses the vaccinia virus capping enzyme and related components to add the 7-methylguanosine cap structure (m7Gppp, Cap 0) to the 5'end of the RNA. In eukaryotes, this structure is closely related to the stability, transport and translation of mRNA. Enzymatically capping RNA is a simple and effective method, which can significantly improve the stability and translation ability of in vitro transcribed RNA for transfection and microinjection.

2. T4 DNA Ligase

T4 DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5'-phosphate and 3'-hydroxyl termini in duplex DNA or RNA with the blunt or cohesive end. The enzyme repairs single-strand nicks in duplex DNA, RNA or DNA/RNA hybrids but has no activity on single-strand nucleic acids.

“As one of the most reliable suppliers of enzyme reagents in the world, it is important for us to enable existing and potential customers to easily obtain high-quality DNA modifying enzymes. We strive to provide our customers and partners with the latest products, services, and technical information, and share our knowledge and expertise in the field of product development and innovation,” said the marketing manager of Creative Enzymes.

More DNA modifying enzyme products can be found at

About Creative Enzymes

Creative Enzymes is a remarkable supplier and manufacturer in the enzymology field. Equipped with an advanced technology platform, Creative Enzymes is able to offer high-quality and professional services to customers. Its products and services are widely used in the academic and pharmaceutical industries.

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