New Diagnostic Enzymes for Kidney and Pancreatic Diseases
Press Release Summary:
- Urease is use to indicate renal failure by measuring urea levels
- Amylase, lipase and trypsin can be used to monitor the relative health of pancreas
- Suitable for structural investigations of carbohydrates and the enzymatic determination of α-amylase
Original Press Release:
Kidney and Pancreas Function Diagnostic Enzymes are Now Available at Creative Enzymes
Creative Enzymes, a global leader in diagnostic enzyme manufacturing and supply, is dedicated to offering a wide range of enzyme products as well as customized enzyme-related services for medical and research diagnosis. Recently, Creative Enzymes launched kidney and pancreas function diagnostic enzymes for the global market.
The primary function of the kidney is to eliminate waste and excess fluid from the blood by producing urine, while the pancreas is responsible for the production of digestive enzymes and insulins. In most cases, early dysfunctions of the kidneys and pancreas show no obvious symptoms in patients, which can lead to serious effects and damage overall health. Therefore, a strategy for early diagnosis of kidney and pancreas failures has attracted intense medical and clinical research attention. Creative Enzymes is a leading biotechnology company supporting the development of diagnostic enzymes for kidney and pancreatic diseases.
Pancreatitis is inflammation of the pancreatic tissue, which can be either acute or chronic. Pancreatic enzymes, including amylase, lipase, and trypsin, can be used to monitor the relative health of the pancreas. Damage to the pancreatic tissue, including pancreatitis, can result in upregulated pancreatic enzyme concentrations, whereas downregulated enzyme levels are associated with exocrine pancreatic insufficiency.
Since chemicals, enzymes, and other compounds secreted from the kidney and pancreas are generally stable in quality and quantity, an abnormal presence of specific entities or elevated levels of enzymes in fluids can be read as an indicator of kidney or pancreas dysfunction or failure. For example, inflammation of the kidney leads to upregulated amylase accumulation in the blood, which can be determined by the maltase and glucoamylase enzymes. Urease is a critical enzyme used to indicate renal failure by measuring urea levels.
Featuring kidney & pancreas function diagnostic enzymes at Creative Enzymes are listed as follows:
Native Rhizopus sp. Glucoamylase
Glucan 1,4-alpha-glucosidase is an enzyme located on the brush border of the small intestine with the systematic name: 4-alpha-D-glucan glucohydrolase. This enzyme catalyzes chemical reactions such as: Hydrolysis of the terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with the release of beta-D-glucose.
Native Microorganism α-Glucosidase (MALTASE)
Native Microorganism α-Glucosidase is useful for structural investigations of carbohydrates and the enzymatic determination of α-amylase when coupled with hexokinase and G-6-P dehydrogenase.
Native Jack bean Urease
Functionally, ureas belong to the superfamily of amidohydrolases and phosphotriesterases and are enzymes that catalyze the hydrolysis of urea into carbon dioxide and ammonia. The hydrolysis reaction occurs as follows: (NH2)2CO + H2O → CO2 + 2NH3.
“Our team comprises experts in enzymology, microbiology, immunology, and pharmacology with years of experience in academia and industry. We can help you not only with the discovery of novel diagnostic enzymes but also with product development. Moreover, we would like to take care of your performance optimization for diagnostic enzymes via different approaches,” stated the executive vice president of Creative Enzymes.
About Creative Enzymes
Creative Enzymes is a remarkable supplier and manufacturer of diagnostic enzymes. Equipped with an advanced technology platform, Creative Enzymes is able to offer high-quality and professional products and services for research customers from medical and clinical diagnosis.
Address: Shirley, NY 11967, USA