Mass Spectrometers offer protein identification capabilities.

Press Release Summary:



Suited for proteomics and metabolism applications, LTQ Orbitrap Discovery(TM) offers MSn ability and label-free profiling for differential expression. It provides up to 30K resolution power, enabling separation of trace level isobaric analytes. LTQ Orbitrap XL features 100 K resolution power and incorporates HCD octapole collision cell for flexibility in MS/MS fragmentation applications including iTRAQ(TM)-based peptide quantitation, PTM analysis, and metabolomics research.



Original Press Release:



Breakthrough LTQ Orbitrap Platform Extended with Two New Mass Spectrometers



Chromatography and Mass Spectrometry

May 31 2007 -- Thermo Fisher Scientific Inc., the world leader in serving science, has extended its innovative range of Thermo Scientific life science hybrid mass spectrometry with the introduction of two new instruments, the LTQ Orbitrap Discovery(TM) and the LTQ Orbitrap XL(TM). Offering outstanding mass accuracy, resolving power, dynamic range and sensitivity, these hybrid instruments offer significant advantages over Q-TOF instruments, both in terms of superior protein identification capabilities and increased sensitivity. The new LTQ Orbitrap instruments are ideally suited for research performed in commercial and academic laboratories for pharmaceutical, metabolomics, proteomics and biomarker discovery. The new instruments will be displayed at the downtown Marriott Ballroom 5, daily from 7:00 - 10:00 PM during the 55th Annual ASMS Conference on Mass Spectrometry, June 3-7 in Indianapolis, IN.

The new Thermo Scientific LTQ Orbitrap Discovery provides accessibility to the breakthrough LTQ Orbitrap technology for a wide range of labs. The robust, powerful and cost-effective system is ideally suited for general proteomics and metabolism applications, offering a superior alternative to Q-TOF systems. Featuring high resolution and excellent accurate mass capabilities, this hybrid LC-MS system achieves high throughput label-free profiling for differential expression while the MSn capability makes the instrument ideal for small molecule characterization and structural elucidation. The LTQ Orbitrap Discovery is a highly sensitive system with up to 30K resolution power and an exceptional scan rate, enabling the separation of trace level, isobaric analytes.

The new Thermo Scientific LTQ Orbitrap XL is the ultimate protein identification and biomarker discovery platform featuring unsurpassed sensitivity in MS and MSn, rapid scan rate, high mass accuracy and up to 100K resolution power. Based on the highly successful LTQ Orbitrap platform, this instrument provides unrivalled performance and flexibility. The LTQ Orbitrap XL features the new HCD octapole collision cell for increased flexibility in MS/MS fragmentation applications including iTRAQ(TM)-based peptide quantitation, PTM analysis, de novo sequencing and metabolomics research. This proteomics platform is also compatible with, and upgradeable to use the Electron Transfer Dissociation (ETD) option for controlled dissociation of peptides and proteins, making this instrument indispensable for advanced proteomics research.

For more information about the new Thermo Scientific LTQ Orbitrap Discovery and LTQ Orbitrap XL mass spectrometers, call +1 800-532-4752, e-mail analyze@thermofisher.com or visit www.thermo.com/orbitrap.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, enabling our customers to make the world healthier, cleaner and safer. With an annual revenue rate of more than $9 billion, we employ 30,000 people and serve over 350,000 customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as environmental and industrial process control settings. Serving customers through two premier brands, Thermo Scientific and Fisher Scientific, we help solve analytical challenges from routine testing to complex research and discovery. Thermo Scientific offers customers a complete range of high-end analytical instruments as well as laboratory equipment, software, services, consumables and reagents to enable integrated laboratory workflow solutions. Fisher Scientific provides a complete portfolio of laboratory equipment, chemicals, supplies and services used in healthcare, scientific research, safety and education. Together, we offer the most convenient purchasing options to customers and continuously advance our technologies to accelerate the pace of scientific discovery, enhance value for customers and fuel growth for shareholders and employees alike. Visit www.thermofisher.com.

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