Low Evaporation Plates eliminate well-to-well variability.

Press Release Summary:




Suited for cell-based arrays, Nunc(TM) Edge 96-well Plates incorporate large perimeter evaporative buffer zones that reduce overall plate evaporation rate to less than 2% after 7 days of incubation. Zones enable use of all 96 wells, minimizing edge effect. Prevention of cell death and toxicity in plates' outer wells allows results to remain true to population phenotype for high-throughput analysis. By eliminating occurrence of chromatic aberrations, flatness of plates optimizes automated imaging.



Original Press Release:



Thermo Fisher Scientific Introduces Low Evaporation Plates for Cell Culture and High Content Analysis



Thermo Scientific Nunc Edge Plates Eliminate Well-to-well Variability

MILFORD, Mass., - Thermo Fisher Scientific Inc., the world leader in serving science, today announced the Thermo Scientific Nunc Edge 96-well Plates for cell-based assays. The new Nunc(TM) Edge plates incorporate large perimeter evaporative buffer zones that eliminate well-to-well variability, while dramatically reducing the overall plate evaporation rate to <2 percent after 7 days of incubation. As a result, more viable and healthy cell yields are obtained. These zones enable the use of all 96 wells, greatly reducing the edge effect commonly experienced in cell culture, while maintaining data consistency throughout the plate.

A minimal volume loss of 10 percent can concentrate media components and metabolites enough to alter cell physiology, a phenomena which is more pronounced in the outer and corner wells. The Nunc Edge plates significantly reduce its occurrence, effectively maintaining sample concentrations over long periods of incubation. The prevention of cell death and toxicity in the plates' outer wells allows results to remain more true to the population phenotype for more efficient, high throughput analysis.

For high content analysis applications, the Nunc Edge plates offer outstanding flatness and superior image quality. In cell-based assays where multiple targets are simultaneously imaged, all the fluorescence from a single location needs to focus at the same point within the imaging system. The flatness of the Edge Plates eliminates the occurrence of chromatic aberrations, enabling efficient automated imaging. Furthermore, varying reagent concentrations from assay washing/aspiration steps are also dramatically reduced.

Combining advanced optical properties with a low evaporation rate, the Thermo Scientific Nunc Edge Plates enable researchers to obtain quality data from automated fluorescence imaging and quantitative analysis protocols. For more information, please visit http://www.thermoscientific.com/edgeplate.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of more than $10 billion, we have approximately 35,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.

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