Liquid Chromatography Systems provide full automation.

Press Release Summary:

Featuring intuitive and intelligent design, Prominence-i and Nexera-i Systems deliver efficient workflow for conventional to ultra-high-speed analysis. Data acquired by Interactive Communication Mode is sent to lab's datacenter by LabSolutions network and managed uniformly by server. i-Series allows direct injection of highly concentrated samples without dilution, supports high-speed multi-analyte processing with 14 sec injection cycle time, and provides repeatability of 1% or less.

Original Press Release:

Shimadzu's New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities

Innovative, intuitive and intelligent functionality advances HPLC for labs of the future

COLUMBIA, Md. — Shimadzu Scientific Instruments has introduced two new integrated liquid chromatography systems, Prominence-i and Nexera-i, adding to the company’s extensive line-up of HPLC and UHPLC systems. Combining excellent functionality, an intuitive operating environment, and full automation, the i-Series provides excellent performance and a more efficient workflow for conventional to ultra-high-speed analysis. 

The i-Series systems feature innovative, intuitive and intelligent design so users can begin building the lab of the future. Through the integration of these systems with LabSolutions software, Shimadzu fosters a new relationship between users and instrumentation. The data acquired by the Prominence-i and Nexera-i via interactive communication mode (ICM) is sent to a lab’s data center by the LabSolutions network and managed uniformly by a server.

ICM allows users to perform operations such as purging mobile phases and confirming analytical results from anywhere in the facility with a smart device. It also permits easy access to a system installed in a closely supervised area such as under a hood where highly active ingredients are being analyzed.

The i-Series’ fundamental functions ensure maximum reliability and stability during testing. In addition to the temperature control function in flow cells, the systems harness new technology for detector optical systems called TC-Optics, which provides excellent baseline stability. This ensures high precision of validation and quantitation of trace components.

The i-Series also allows the direct injection of highly concentrated samples without dilution. Even when injecting ultra-low sample volumes, the systems provide repeatability of 1 percent or less. In addition, by supporting high-speed multi-analyte processing with a 14-second injection cycle time, the i-Series achieves processing speeds more than twice as fast as previous Shimadzu systems and almost three times faster than other systems.

Users can also achieve easier operation with the i-Series thanks to LabSolutions. The uniform graphical user interface on both the integrated touch screen and the LabSolutions computer screen allows users to easily create analytical methods using the same workflow. Additionally, the quick batch function simplifies batch file creation by permitting users to create batch files while checking the vial positions through the window.

The i-Series smart features also increase work efficiencies for users while providing a built-in ECO mode for saving costs. The entire series of analytical operations can be automated from system startup, including mobile phase purging, column equilibration in preparation for starting measurements, and starting and shutting down analysis. Operations for routine analysis such as injecting samples based on test results can also be automated.

The i-Series can be used for a wide range of industries such as pharmaceutical, biopharmaceutical, chemical, environmental, food, and academic teaching.    

For more information on Shimadzu’s i-Series, visit

About Shimadzu Scientific Instruments Inc.

Shimadzu Scientific Instruments (SSI) is the American subsidiary of Shimadzu Corp., headquartered in Kyoto, Japan. Founded in 1875, Shimadzu is a $3 billion multinational corporation with three major divisions: Medical Diagnostics, Aerospace/Industrial and Analytical Instruments. In the United States, SSI has a network of more than 50 locations providing local and regional sales, service and technical support. Visit for more information.

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