LIMS Software supports in vitro ADMET experiments.

Press Release Summary:




Galileo LIMS(TM) v3.2 allows users to design, calculate, and report data from metabolic stability, drug-drug interaction, protein binding, permeability, and enzyme kinetics studies. In addition to user-definable study types and customizable calculations, program provides decision trees that allow user to define scenarios under which flagged results require further review. Users can filter data sets and flag data based on comments entered during analytical data review.



Original Press Release:



Thermo Enables Greater Flexibility for ADMET Studies with Galileo LIMS v 3.2



Philadelphia, PA (May 22, 2006) - Thermo Electron Corporation, the leading provider of analytical instruments and laboratory information management systems (LIMS), today announced enhancements to its Galileo LIMS(TM), providing greater flexibility for high throughput ADMET experiments that facilitate lead optimization in drug discovery.

Galileo is a LIMS designed specifically to support in vitro ADMET experiments, allowing users to design, calculate and report data from metabolic stability, drug-drug interaction, protein binding, permeability and enzyme kinetics studies. Version 3.2 now gives users greater control over the assays performed with user-definable study types and customizable calculations.

"Galileo 3.2 expands in vitro research capabilities by enabling the full range of ADMET assays via user-definable calculations," said Dave Champagne, vice president and general manager of Thermo's informatics business. "We continue to enhance Galileo with off-the-shelf functionality that users need to keep the study design flexible, while providing the benefits of a more standard approach to assay management, analysis, storage and reporting of the data."

In addition to user-definable study types to increase flexibility, Galileo now offers user-configurable decision trees that allow the user to define scenarios under which flagged results require further review. Questionable data is quickly reviewed with a new ability to filter data sets and to flag data based on comments entered during analytical data review. Templating of design and output parameters, as well as result flagging, eliminates manual actions, saving time and reducing errors for users. For details on enhancements in Galileo 3.2, visit www.thermo.com/lims.

Galileo LIMS is offered as an alternative to manual calculations using spreadsheets, resulting in disparate files maintained in many locations in multiple file formats. The LIMS enables drug discovery researchers to conduct high throughput in vitro screening and profiling of compounds to determine at an earlier and less costly stage which compounds might develop into commercially viable therapeutic drugs. Galileo enhances the value of its acquired data by ensuring consistency of the ADME calculations and uploading to a corporate database for broad dissemination and use.

Please send all leads from this editorial FAO: Kathleen Beaulieu on e-mail marketing.informatics@thermo.com

For more information please call Thermo Electron on 866-463-6522 or e-mail marketing.informatics@thermo.com

About Informatics
Thermo is the worldwide leader in laboratory software and related services, providing enterprise-wide, multi-laboratory solutions that have become the corporate standard at leading organizations. Our LIMS and CDS are facilitating laboratory data in the world's leading pharmaceutical companies, petrochemical and chemical plants, food and beverage manufacturers, and other major industries. To support our global installations, Thermo provides implementation, validation, training, maintenance and support from the industry's largest worldwide informatics services network.

About Thermo Electron Corporation
Thermo Electron Corporation is the world leader in analytical instruments. Our instrument solutions enable our customers to make the world a healthier, cleaner and safer place. Thermo's Life and Laboratory Sciences segment provides analytical instruments, scientific equipment, services and software solutions for life science, drug discovery, clinical, environmental and industrial laboratories. Thermo's Measurement and Control segment is dedicated to providing analytical instruments used in a variety of manufacturing processes and in-the-field applications, including those associated with safety and homeland security. For more information, visit www.thermo.com

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