Light Scattering Detector analyzes pharmaceutical compounds.

Press Release Summary:




Evaporative Light Scattering Detector, Model PL-ELS 2100, is available with optional Integrated Cooled Evaporator, Model PL-ELS 2100 Ice, which operates at temperatures down to 10°C to meet requirements for pharmaceutical analysis of non-UV absorbing, low molecular weight, semi-volatile analytes. Addition of evaporation gas not only allows low temperature operation with aqueous mobile phases, but also facilitates removal of water at sub-ambient temperatures.



Original Press Release:



New Evaporative Light Scattering Detector for Enhanced Detection of Semi-Volatile Compounds, PL-ELS 2100 Ice



For improved analysis of pharmaceutical compounds at low temperatures, Polymer Laboratories, now a part of Varian, Inc. (Nasdaq:VARI), has launched a new option for its highly acclaimed PL-ELS 2100 Evaporative Light Scattering Detector (ELSD), the PL-ELS 2100 Ice (Integrated Cooled Evaporator).

In order to meet the requirements for pharmaceutical analysis of non-UV absorbing, low molecular weight semi-volatile analytes, for example, drug candidates, ELSDs must be operated at low temperatures in order to maximize detection for these compounds. To reduce the operating temperature to below ambient for low molecular weight, low boiling point compounds, e.g. short chain hydrocarbons, Polymer Laboratories has introduced the unique option of sub-ambient operation to provide greater sensitivity.

The PL-ELS 2100 Ice operates at temperatures down to 10°C. The detector applies a stream of dry nitrogen during the evaporation step to reduce the relative humidity of the surroundings. The addition of evaporation gas not only allows low temperature operation with aqueous mobile phases but also facilitates the removal of water at sub-ambient temperatures. This provides high sensitivity detection of semi-volatile compounds and a more universal response across all compounds.

For further information, please contact:
Polymer Laboratories, now a part of Varian, Inc., Varian, Inc., Amherst Fields Research Park, 160 Old Farm Road, Amherst, MA 01002, tel 413 253 9554, fax 413 253 2476, email PLInfo@polymerlabs.com, www.polymerlabs.com.

About Varian, Inc.
Varian, Inc. is a leading worldwide supplier of scientific instruments and vacuum technologies for life science and industrial applications. The company provides complete solutions, including instruments, vacuum components, laboratory consumable supplies, software, training, and support through its global distribution system. Varian, Inc. employs approximately 3,700 people and operates manufacturing facilities in 14 locations in North America, Europe, and the Pacific Rim. Varian, Inc. had fiscal year 2005 sales of $773 million (excluding the divested Electronics Manufacturing business), and its common stock is traded on Nasdaq under the symbol, "VARI". Further information is available on the company's Web site: www.varianinc.com.

About Polymer Laboratories Ltd.
Founded in 1976, Polymer Laboratories Ltd. specializes in the development of techniques and instrumentation for the characterization of polymer systems and the development of high technology polymer particles for application in the fields of chromatography, diagnostics and life science. The company's main design and manufacturing facilities operate out of Shropshire in the UK, and employ some 160 people. Varian, Inc. acquired Polymer Laboratories in November 2005. Additional information about Polymer Laboratories is available at www.polymerlabs.com.

Registered Office: Essex Road, Church Stretton, Shropshire SY6 6AX, UK
Registered in England No. 2948069

Now a part of Varian, Inc.

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