Knife Mill grinds coated tablets for analysis.

Press Release Summary:

Grindomix GM 200 is able to grind 20 gelatin-coated tablets in a few seconds, providing homogenous sample for analysis. It features feed size of 10-40 mm and produces final fineness down to approximately 0.3 mm. Parameters can be set for reproducible results. Grindomix GM 200 is particularly suitable for grinding larger tablets and plants with high fat or moisture content.

Original Press Release:

Optimal Grinding of Coated Tablets with the Grindomix GM200 from Retsch

When preparing tablets and capsules for the subsequent analysis of their active substances, it is important that the individual tablets are ground up to provide a homogeneous sample mixture. Care should be taken to ensure that the size reduction process does not cause any alteration to, or contamination of, the individual active substances. This is an important criterion when selecting a laboratory mill.

The grinding of coated tablets places special demands on
laboratory mills. The coating is usually made from sugar solutions or gelatin. If mortars or ball mills are used for size reduction then this type of tablet tends to clump because of the unsuitable mechanical stress and produces an inadequate, inhomogeneous sample mixture. Thus, a mill is required that avoids this clumping.

For such applications the Retsch Knife Mill Grindomix GM 200 has
proven itself exceptionally well in practice. The GM 200 is able to grind 20 gelatin-coated tablets in a few seconds with outstanding results and to provide a homogeneous sample for analysis.

Other Retsch mills that can be used for the comminution of homeopathic and other tablets are the Mixer Mill MM 301, the Ultra-Centrifugal Mill ZM 200 and the Mortar Grinders RM 100 and KM 100. These mills allow each pharmaceutical laboratory to prepare samples of tablets and capsules for analysis in an efficient and economic way.

Features of the GM 200:
The Knife Mill Grindomix GM 200 is particularly suitable for grinding larger tablets and plants with a high fat or moisture content
o Feed size 10 - 40 mm
o Final fineness down to approx. 0,3 mm
o Parameter setting for reproducible results
o Comprehensive accessories for versatile use

Retsch is a global company dedicated to providing novel technologies and high quality tools for the sample preparation of solids used in R&D and QA applications as well as small-
scale production. For more information about Retsch's complete product line of mills and grinders, sample dividers, sieve shakers and test sieves, and optical particle sizers contact
Retsch, Inc. at 74 Walker Lane, Newtown, PA 18940, USA, Toll-Free: 1-866-4-RETSCH (1-866-473-8724); Fax: (267) 757-0358; E-mail: info©; Internet:

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