Chromatography Column is stable at extreme temperatures.

Press Release Summary:




Blaze200(TM) consists of polydentate silica phase that provides temperature stability for use up to 200°C and pH conditions as high as 12. It integrates multiple point attachments to silica with cross-linking, creating barrier over silica backbone, protecting it from hydrolytic attack. Column offers traditional C18 selectivity, and is suited for isothermal and programmed separations over wide ranges of temperature.



Original Press Release:



Blaze Away with Selerity Technologies' New Column



SALT LAKE CITY, Utah (April 7, 2005) - Temperature Programmed Liquid Chromatography (TPLC) specialist, Selerity Technologies Inc introduces a new silica-based stationary phase that can withstand temperatures up to 200ºC. The new Blaze200(TM) column opens up a range of new opportunities for the separations scientist looking to take advantage of better results and peak shapes. This novel advancement in column technology means that most barriers preventing the use of extreme temperature in HPLC can now be overcome.

Although there are a variety of stationary phases such as polymeric and graphitic carbon materials that can be used at elevated temperatures, most HPLC chemists prefer the selectivity and higher efficiencies of silica-based columns. Increasing temperature can drastically limit the column lifetime when the bonded phase is based on traditional chemistries. Most silica-based HPLC columns can only be used to temperatures up to 60°C and a pH range of 3-8. Such columns have a propensity to degrade as water attacks the underlying support particles.

Selerity's new Blaze200 column overcomes these obstacles. It consists of a new polydentate silica phase that is stable at extreme temperatures, with added pH stability. The development of a new polycarbosilane bonding chemistry that is hydrolytically stable against breakdown in aqueous environments facilitates such analyses. It integrates multiple point attachments to the silica with a high degree of cross-linking. This combination creates a highly protective barrier over the silica backbone, protecting it from hydrolytic attack.

The column offers traditional C18 selectivity, while providing enhanced temperature stability for use up to 200°C and pH conditions as high as 12. Columns based on this chemistry are useful for both isothermal and programmed separations over wide ranges of temperature.

For more information about Selerity's new silica stationary phase and TPLC method development, please visit www.selerity.com or e-mail sales@selerity.com.

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