Bruker Announces High-Performance and Cost-Effective NMR Solutions for the Pharmaceutical and Chemical Industries
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PITTSBURGHÂ – At the 57th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker (NASDAQ: BRKR) is showcasing several innovative drug discovery, drug development and process control solutions for small molecule NMR characterization in the chemical and pharmaceutical industries.
   -- AssureNMR with CRAFT: Now available with Complete Reduction to
       Amplitude Frequency Table (CRAFT) and tools for biologics analysis
       AssureNMR™ 2.1 reveals small structural and compositional changes in
       complex materials such as biofluids, culture media and biologics,
       important for product quality control. CRAFT delivers matching and
       quantification of key metabolites, based on targeted fingerprinting.
       Metabolite identification is enhanced in AssureNMR by the ability to
       incorporate the large, public Human Metabolome Data Base (HMDB) and
       DrugBank database, each containing over 900 NMR spectra of metabolites
       and drug compounds, respectively. Anthony Ribeiro, Ph.D., of Duke
       University Medical Center said: "These features represent major
       enhancements to the AssureNMR software package for the detailed analysis
       of biofluid systems."
   -- Experiment Selector: The latest release of TopSpin® software,
       TS3.5pl6, features a new, user-friendly GUI which provides easy access
       to vast experiment libraries including standard Bruker pulse sequences
       and user generated experiment libraries for both industrial and academic
       users. The GUI enables users to build and organize their own customized
       experiment libraries via simple drag and drop, provides multiple options
       for experiment setup and optimization, enables script based parameter
       adjustment, and makes the setup of sophisticated experiments simple and
       efficient. Â
   -- Free TopSpin Processing: In order to provide students, instructors and
       researchers with unlimited access to the best tools for off-line NMR
       processing, Bruker is making their market leading NMR processing
       software TopSpin available free of charge for all academic users. In
       addition to Bruker NMR data, the software is able to process data
       acquired on Agilent, Varian and JEOL systems, and it can read data
       provided in JCAMP format. For a download of TopSpin software, please go
       to: www.bruker.com/TopSpin-Processing
   -- SmartDriveNMR: Bruker is setting new standards for NMR solutions with
       its 'Intelligent NMR Spectrometer Initiative'. The goal of this project
       is to incorporate automatic, intelligent decision making into the
       spectrometer. SmartDriveNMR - the further step in this direction -
       decides on-the-fly for an optimized set of NMR experiments delivering
       the most information with the best quality within a user defined
       timeframe for a given spectroscopic problem. SmartDriveNMR saves
       spectrometer time by automatically running only these experiments that
       add the most value to solve a given problem. SmartDriveNMR is
       seamlessly integrated into the industry-standard routine NMR acquisition
       software IconNMR to provide solutions for structure consistency
       analysis, which are common in most NMR service labs.
   -- Lab2NMR: This adaption of the automation and scheduling system
       lab2lab™ (www.ttplabtech.com) allows NMR samples in modern, larger
       analytical service organizations to be transported to the instrument via
       the lab2lab pipe system. Samples are submitted for analysis directly
       from the chemist's bench in standard vials. The lab2lab system
       transports these vials to remote analytical NMR instrument via a pipe
       system. Once at the instrument, lab2NMR accepts the sample, prepares it
       for NMR measurement and schedules the experiment. This system improves
       the efficiency and the load-factor, thus enhancing NMR productivity.
   -- Dr. Harald Schröder at Novartis Basel stated: "With the latest addition
       of Lab2NMR, our well established lab2lab system for rapid, flexible and
       hassle-free open access routine analytics became even more productive.
       Now, chemists can send off samples for NMR analysis as easily and with
       the same interface as they are used to from LC-MS. The resulting
       spectra are in their inbox much faster than previously, when the chemist
       had to find the closest available open access system."
   -- New Automation Tools: The new SampleCase-heated is designed for work in
       polymer research. It is capable of keeping up to 24 samples at
       temperatures of up to 125°C, keeping polymers liquid and ready for
       measurement. Bruker also announces the next-generation cooling rack for
       the SampleJet autosampler. This new module allows for individual cooling
       and temperature regulation of each of the five sample racks. With the
       additional 96 spinner-less open access sample positions, the SampleJet
       is the best choice for metabolomics and bio-screening applications.
   -- Bruker Fusion-SV 1.1: The new edition of the Bruker Fusion-SV 1.1
       automated structure verification solution for small molecules in pharma
       and chemistry research integrates high-resolution, accurate mass
       ESI-QTOF mass spectrometry for automated chemical formula generation
       with NMR spectroscopy. The updated Bruker Fusion-SV 1.1 solution now
       includes additional 2D NMR methods for even higher confidence in rapid,
       automated structure verification. Designed for the workflow of
       medicinal and synthetic chemists in pharma, chemical industry or in
       academia, Bruker Fusion-SV 1.1 guides chemists to meaningful results
       with minimal interactions and without the need for expert knowledge.
   -- InsightMR: Designed for the optimization of chemical reactions under
       process conditions, the new InsightMR™ solution uses on-line NMR
       monitoring to enhance process understanding. InsightMR has a new flow
       unit with temperature-controlled transfer lines to enable fast and
       continuous transfer of reaction mixtures from a vessel to the
       spectrometer. InsightMR software features a user-friendly interface to
       allow both expert and non-expert NMR users to set up experiments in
       deuterated and non-deuterated solvents and optimize acquisition
       parameters on-the-fly, based on real-time kinetic data.
   -- Fourier 300 HD: In 2010, Bruker introduced its successful entry-level
       NMR system, the Fourier 300. Based on the positive customer response,
       we now introduce an improved version, the Fourier 300 HD. Derived from
       our renowned Avance III HD electronics, the Fourier 300 HD provides an
       entry level, two-channel system for proton and carbon operation for
       budget-conscious customers. The system is equal in specifications to
       our Avance series and is operated by TopSpin software. With its small
       footprint and freely available TopSpin Processing software (limited to
       academic users), the Fourier 300 HD is an excellent system for education
       and smaller routine labs.Â
Werner E. Maas, Ph.D., President of the Bruker BioSpin MRS Division, commented: "In addition to developing high field magnets, such as our new Aeon 1 GHz magnet, and new, highly sensitive X-nucleus direct detection CryoProbes, we also focus our RD on tools that make our customers successful by enhancing their productivity or expanding their range of NMR applications. In addition to introductions for sample handling and data analysis, we started the Intelligent NMR Spectrometer Initiative, a multi-year program to enhance productivity and ease-of-use of our spectrometers. SmartDriveNMR and lab2NMR are just two of the early results of this program."
About Bruker Corporation
For more than 50 years, Bruker has enabled scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high-performance scientific research instruments and high-value analytical solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels.
In close cooperation with our customers, Bruker is enabling innovation, productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy, nano-analysis and industrial applications, as well as in cell biology, preclinical imaging, clinical research, microbiology and molecular diagnostics. For more information, please visit www.bruker.com.
For more information on Bruker at ENC 2016, please visit: www.bruker.com/enc.
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Bruker Corporation
ContactT:
Media Contact:
Dr. Thorsten Thiel
Director of Marketing Communications
Bruker Corporation
T: +49 (721) 5161-6500
E: thorsten.thiel@bruker.com
Web Site: http://www.bruker.com
