Axio Scan.Z1 Digital Slide Scanner Achieves Optimal Image Quality

Flexible automated image capture in bright-field and fluorescence

The Axio Scan.Z1, an automated microscope from Carl Zeiss Microscopy, allows researchers to digitalize fixed tissue sections and cytologic specimens in bright-field and fluorescence. Supporting scientists with recurring tasks in the capture of large sample contingents, for example tissue analysis in Alzheimer's and cancer research, the Axio Scan.Z1 is ideal for a range of applications from basic research to tasks in the pharmaceutical industry. As many as 100 microscope slides can be digitalized at one time. 

Using an innovative tray design, the Axio Scan.Z1 captures the entire specimen area of the microscope slide, including the edge. The self-calibrating automated slide scanner presents specimens on high-quality virtual slides just minutes later. For fluorescence applications, filter wheels switch wavelengths in just 50 milliseconds.

Sensitive cameras and maximally corrected optics achieve optimal image quality. Maximum protection for the sample is ensured by the Colibri.2 UV-free LED light source, as well as a focus finder with oblique illumination, called the ring aperture contrast.

Axio Scan.Z1 is operated by ZEISS ZEN imaging software, which allows users to work with pre-defined recording parameters automatically or select all settings individually. The user interface is specially adapted to research workflow. Users decide at the outset how many microscope slides and which detection modes and camera they wish to use, and simply upgrade Axio Scan.Z1 as their tasks expand.

The virtual slides can be organized in the ZEN Browser database, which organizes data online and cross-platform via an intuitive web interface that keeps images filed together with metadata and supporting documents. With ZEN browser, users can also insert annotations and view images in transmitted light and multi-channel fluorescence virtual microscopy photos. The free ZEN browser mobile app for iPad and iPhone allows users to access, view, and share their images and data with colleagues independent of the operating system – even when traveling.

For additional information on the Axio Scan.Z1 please visit


The Carl Zeiss Group is an international leader in the fields of optics and optoelectronics. In fiscal year 2011/12 the company’s approximately 24,000 employees generated revenue of nearly 4.2 billion euros. In the markets for Industrial Solutions, Research Solutions, Medical Technology and Consumer Optics, ZEISS has contributed to technological progress for more than 160 years and enhances the quality of life of many people around the globe. The Carl Zeiss Group develops and produces planetariums, eyeglass lenses, camera and cine lenses and binoculars as well as solutions for biomedical research, medical technology and the semiconductor, automotive and mechanical engineering industries. ZEISS is present in over 40 countries around the globe with about 40 production facilities, over 50 sales and services locations and approximately 20 research and development sites. Carl Zeiss AG is fully owned by the Carl Zeiss Stiftung (Carl Zeiss Foundation). Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany.


The Microscopy business group at ZEISS is the world’s only manufacturer of light, X-ray and electron microscopes. The company’s extensive portfolio enables research and routine applications in the life and materials sciences. The product range includes light and laser scanning microscopes, X-ray microscopes, electron and ion microscopes and spectrometer modules. Users are supported for software for system control, image capture and editing. The Microscopy business group has sales companies in 33 countries. Application and service specialists support customers around the globe in demo centers and on site. The business group is headquartered in Jena, Germany. Additional production and development sites are in Oberkochen, Göttingen and Munich, as well as in Cambridge in the UK and Peabody, MA and Pleasanton, CA in the USA. The company has around 2,800 employees and generates revenue of 650 million euros.

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