Separation Columns enable peptide analysis and isolation. December 5, 2006 -
Based on C18 BEH Technology(TM), Peptide Separation Technology columns separate wide range of peptides, large and small, acidic and basic, as well as hydrophobic and hydrophilic. Columns provide protein digest separations, peptide mapping, and ability to quantify trace peptide variants in peptide mapping. Available in lengths of 50-250 mm, columns are available in 1.7-10 µm particle size range, particle pore sizes of 130 or 300 Å, and internal diameters of 75 µm to 30 mm.
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Original Press release
Waters Corp.
34 Maple St.
Milford, MA, 01757
USA
Waters Corporation Introduces New Line of Peptide Separation Columns
New Columns for Peptide Analysis and Isolation
Milford, Mass., November 14, 2006 - Waters Corporation has introduced new columns for peptide analysis and isolation based on its proprietary C18 BEH Technology(TM) particle platform. The new Peptide Separation Technology columns are available in a 1.7µm - 10µm particle size range, lengths from 50 to 250mm and internal diameters (ID) of 75µm to 30mm. Waters is taking orders for custom prepared columns as well. Nominal particle pore sizes are either 130 or 300Å pore sizes, with plans to deliver the larger 300Å pore size columns in November of '06.
These columns are intended for proteomics applications, peptide mapping of biopharmaceuticals, and for the characterization and purification of synthetic peptides.
The new Peptide Separation technology columns, in combination with all Waters HPLC Systems, ACQUITY UPLC(TM) and nanoACQUITY UPLC(TM) instruments, the columns offer scientists many benefits including improved separation of protein digests, significantly improved peptide mapping, efficient glycopeptide separations, and ability to quantify trace peptide variants in peptide mapping.
Specifically the Peptide Technology Separation columns improve the chromatography of peptides by offering scientists narrow and symmetrical peaks for best resolution; broad applicability by separating a wide range of peptides, both large and small, acidic and basic, hydrophobic and hydrophilic; and excellent peak shape and retention in formic acid and trifluoroacetic acid.
Peptide Separation Technology columns are integral elements of Waters Assured Performance Solutions; a combination of instrumentation, chemistry, and software optimized for particular applications. More information on these columns is available at waters.com/pst
Peptides are short sequences of amino acids derived from proteins usually by enzymatic digestion. By mapping, or separating and quantifying, individual peptides, life scientists can learn a significant amount about the identity and structure of specific protein molecules like human insulin.
Central to successful peptide analysis are tools like liquid chromatography - often in combination with mass spectrometry - and analytical columns and chemistries specifically designed for peptide applications.
About Waters Corporation (www.waters.com)
Waters Corporation holds worldwide leading positions in three complementary analytical technologies - liquid chromatography, mass spectrometry and thermal analysis. These markets account for approximately $5.0 billion of the overall $20 - $25 billion analytical instrument market.
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