Particle Analyzers image encapsulated Paclitaxel.
April 10, 2012 -
By taking digital images of individual particles of encapsulated Paclitaxel, FlowCAM® PV Series detects presence of aggregates in cancer treatment formulation and permits testing and assessment of drug delivery carriers and methods. Particles are characterized in real-time with up to 32 different parameters. Capable of detecting particle from 2-800 µm with samples as small as .1 ml, analyzers save images and corresponding data with cGMP date/time stamp as tiff or jpeg files.
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Original Press release
Fluid Imaging Technologies
65 Forest Falls Dr.
Yarmouth, ME, 04096
USA
Patented Particle Analysis Technology Images Encapsulated Paclitaxel to Reveal Aggregates, Assess Drug Delivery Carrier
FlowCAM® PV Series Supports Cancer Drug Delivery Safety, Efficacy
Yarmouth, ME: The new FlowCAM® PV Series imaging particle analysis system from laboratory instrumentation manufacturer Fluid Imaging Technologies, Yarmouth, Maine (www.fluidimaging.com) automatically takes high-resolution, digital images of individual particles of encapsulated Paclitaxel to detect the presence of aggregates in the cancer treatment formulation and permit testing and assessment of drug delivery carriers and methods such as intravenous drip, emulsion, liposome and microsphere.
Invaluable for documenting the safety of Paclitaxel in parenterals and for monitoring particulates in coatings on stents, catheters and other medical devices, the FlowCAM reveals both the Paclitaxel and its carrier in full color and measures each particle based on the actual size and shape as imaged. The particles are characterized in real-time with up to 32 different parameters including advanced morphological properties such as perimeter, roughness, elongation and compactness, along with a host of traditional properties such as size, length, aspect ratio and ESD.
Detecting thousands of particles in a sample in less than a minute, the FlowCAM PV-40 and FlowCAM PV-100 Particle Vision series particle analyzers save the images and corresponding data with a cGMP date and time stamp as tiff or jpeg files for easy review and emailing to colleagues. The FlowCAM biopharmaceutical instrumentation excels at detecting particles ranging from 2 um to 800 um in size even with samples as small as .1 ml. Paclitaxel is also sold as Taxol, Abraxane®, Apo-Paclitaxel®, Aclixel, Asotax, Bristaxol, Bryoxet and Praxel.
For more information and live demonstration, contact Faith Baker, Fluid Imaging Technologies, Inc.; 65 Forest Falls Drive, Yarmouth, ME 04096; 207.846.6100.; Fax 207.846.6110; www.fluidimaging.com; faith@fluidimaging.com.
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