Optical Biosensors detect pH, CO2, and O2.

Press Release Summary:

Fluorescence-based Optical Biosensors measure typical blood gas parameters in tissue engineering, organ perfusion, and general physiology applications. Units are inherently self-referencing, eliminating potential for measurement error arising from changes in sample properties over duration of experiment. Shipped pre-calibrated, USP Class VI-certified sensors are completely sterilizable and require no electrolytes, membrane chanes, or pre-polarization of electrode amplifier.

Original Press Release:

New Fluorescence-Based Detection of pH, CO2 and O2

This NEW Fluorescence-based optical Biosensor from Harvard Apparatus represents a breakthrough technology in the measurement of typical blood gas parameters in tissue engineering, organ perfusion and general physiology applications. Features include:
o More accurate measurements than traditional methods
o Sensitive sensors are also rugged for long life
o No electrolytes required
o Completely sterilizable sensors
o USP Class VI-certified sensors are shipped pre-calibrated
o Minimal chemical degradation means usage life and infrequent recalibration In contrast to traditional ion-sensitive chemosensors, these optical biosensors use a controlled optical source that emits light signals at specified frequencies which excite an ion-specific sensor spot in contact with the test medium. Changes in the parameter of interest are reported as a proportional change in some characteristic (intensity, phase shift, etc.) of the fluorescence. Because they are inherently self-referencing, this detection technology eliminates the potential for measurement error arising from changes in sample properties (i.e. flow rate, viscosity, etc.) over the duration of an experiment. This ensures stable, drift-free calibration and hence reliable measurements throughout the lifespan of a sensing element. Unlike polarographic oxygen electrodes, this technology is non ion-consumptive. These easy-to-use biosensors are free of the maintenance complications inherent in traditional chemosensing: requiring only cleaning and dry storage, there is no need for electrolyte, membrane changes, or pre-polarization of the electrode amplifier. Harvard Apparatus is a global developer, manufacturer and distributor of innovative and specialized products to enhance bioresearch.