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Optical Biosensors detect pH, CO2, and O2.

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Optical Biosensors  detect pH, CO2, and O2.
Optical Biosensors detect pH, CO2, and O2.

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September 12, 2011 - Fluorescence-based Optical Biosensors measure typical blood gas parameters in tissue engineering, organ perfusion, and general physiology applications. Units are inherently self-referencing, eliminating potential for measurement error arising from changes in sample properties over duration of experiment. Shipped pre-calibrated, USP Class VI-certified sensors are completely sterilizable and require no electrolytes, membrane chanes, or pre-polarization of electrode amplifier.
Original Press release

Harvard Apparatus, Inc.
84 October Hill Rd., Bldg. 7
Holliston, MA, 01746 1371
USA



New Fluorescence-Based Detection of pH, CO2 and O2


This NEW Fluorescence-based optical Biosensor from Harvard Apparatus represents a breakthrough technology in the measurement of typical blood gas parameters in tissue engineering, organ perfusion and general physiology applications.

Features include:

o More accurate measurements than traditional methods

o Sensitive sensors are also rugged for long life

o No electrolytes required

o Completely sterilizable sensors

o USP Class VI-certified sensors are shipped pre-calibrated

o Minimal chemical degradation means usage life and infrequent recalibration

In contrast to traditional ion-sensitive chemosensors, these optical biosensors use a controlled optical source that emits light signals at specified frequencies which excite an ion-specific sensor spot in contact with the test medium.

Changes in the parameter of interest are reported as a proportional change in some characteristic (intensity, phase shift, etc.) of the fluorescence. Because they are inherently self-referencing, this detection technology eliminates the potential for measurement error arising from changes in sample properties (i.e. flow rate, viscosity, etc.) over the duration of an experiment. This ensures stable, drift-free calibration and hence reliable measurements throughout the lifespan of a sensing element.

Unlike polarographic oxygen electrodes, this technology is non ion-consumptive. These easy-to-use biosensors are free of the maintenance complications inherent in traditional chemosensing: requiring only cleaning and dry storage, there is no need for electrolyte, membrane changes, or pre-polarization of the electrode amplifier.

Harvard Apparatus is a global developer, manufacturer and distributor of innovative and specialized products to enhance bioresearch.
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