In-Gel Detection Kit locates phosphorylated proteins.July 2, 2007 -
Phosdecor(TM) Fluorescent Phosphoprotein In-Gel Detection Kit identifies Phosphoprotein changes that can indicate many cell signaling processes, cancer, and obesity. It includes phosphate specific PhosDecor Stain, specially formulated buffers, and positive control to validate system performance. Interaction of stain with protein-bound phosphate groups results in selective chemiluminescence detectable with commonly available instruments.
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Original Press release
Sigma Aldrich Corp.
3050 Spruce St.
St. Louis, MO, 63103
USA
Sigma-Aldrich Launches Phosdecor(TM) Fluorescent Phosphoprotein In-Gel Detection Kit
Effective screening is top priority in biomarker discovery community
ST. LOUIS, June 7 // -- Sigma-Aldrich (NASDAQ:SIAL) proudly announces the launch of the PhosDecor(TM) Fluorescent Phosphoprotein In-Gel Detection Kit, a highly sensitive and selective tool for the identification of phosphorylated proteins.
Phosphoprotein changes are implicated in many cell signaling processes, cancer and obesity. Up to 30% of the human proteome may be phosphorylated at any time, and effective electrophoretic screening of phosphoproteins in complex protein samples is a top priority in the biomarker discovery community. Samples including biofluids and tissue extracts can be analyzed and subjected to further proteomic characterization, significantly improving the understanding of how kinome changes occur and what proteins are affected.
The PhosDecor kit includes a phosphate specific PhosDecor Stain, specially formulated buffers and a positive control to validate system performance. Interaction of the PhosDecor stain with protein-bound phosphate groups results in a selective chemiluminescence detectable with commonly available instruments. Some components are also available separately allowing for custom applications.
About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,600 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award- winning Web site at sigma-aldrich.com.
Source: Sigma-Aldrich
CONTACT: Sean Battles of Sigma-Aldrich, +1-314-286-7616, sean.battles@sial.com
Web site: http://www.sigma-aldrich.com/
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