Hydraulic Processor operates at up to 30,000 psi.
March 21, 2008 -
Equipped with ceramic/diamond interaction chamber that allows flow rates up to 450 mL/min at 25,000 psi, Model M-110EH-30 enables production of nano-suspensions and nano-emulsions, as well as liposomal encapsulation and cell disruption. It provides average flow rate (with water) of 320 mL/min, and can handle batch sizes of up to several gallons. Utilizing fixed geometry interaction chamber technology, unit is capable of generating shear rates within product stream.
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Original Press release
Microfluidics, Division MFIC Corp.
30 Ossipee Rd.
Newton, MA, 02464 9101
USA
New Standard Features for Microfluidics M-110EH-30 Microfluidizer® Processor
New Version of the Lab Machine Designed to Operate to 30,000 psi Process Pressure Comes With Both Diamond and Ceramic Interaction Chambers
Newton, Mass. - Microfluidics' latest version of its versatile laboratory model M-110EH Microfluidizer® high-shear processor, the M-110EH-30, now incorporates new capabilities and features into the original system architecture. Designed to operate reliably and efficiently at up to 30,000 psi process pressure, the M-110EH-30 is easily enables the production of nano-suspensions and nano-emulsions, as well as liposomal encapsulation and cell disruption with the least number of passes.
Additionally, the M-110EH-30 now comes standard with both a ceramic and diamond interaction chamber that will allow flow rates up to 450 ml/minute at 25,000 psi, allowing for more efficient processing of pharmaceutical formulations, fine chemicals, and biological material ranging from simple oil-in-water emulsions to highly immiscible solids-in-liquid suspensions. All results from the M-110EH-30 machine are guaranteed to be scaleable to Microfluidics' broad line of M-700 pilot and production machines.
Utilizing Microfluidics' fixed geometry interaction chamber technology, the M-110EH-30 is capable of generating shear rates within the product stream that are orders of magnitude greater than any other fluid processing or mixing equipment on the market. Shear rate imparts the required energy directly to the product stream, safely disrupting bacteria cells and reducing particles and droplets to nanoparticles.
Equipped with a single acting intensifier pump that amplifies the hydraulic pressure at the simple turn of a knob, the M-110EH-30 is able to drive the product stream through the interaction chamber. The machine provides an average flow rate (with water) of 320 ml/min and can handle batch sizes of up to several gallons.
Within the wear-resistant diamond interaction chamber is specially designed fixed-geometry micro channels that accelerate the product stream to high velocities and create high shear and impact forces to achieve the desired results. The system also comes with an interchangeable ceramic interaction chamber for achieving lower pressure applications and for processing of less abrasive formulations. Upon exiting the interaction chamber, the product flows through an onboard heat exchanger that regulates the product to a desired temperature. At this point, the product may be recirculated through the system for further processing or directed externally to the next step in the process.
The system is easy to operate and is designed for clean-in-place and steam-in-place with a steam sterility option. Because the interaction chamber employs no moving parts, no disassembly is required for cleaning.
About Microfluidics
Microfluidics, a wholly owned subsidiary of MFIC Corporation, is a supplier of advanced fluid processing equipment and reaction technology for laboratory, pilot scale and manufacturing applications. The equipment enables the manufacture and formulation of numerous nanomaterials and nanoscale products and produces the most uniform and smallest liquid and suspended solid structures available.
Microfluidics has been a worldwide supplier of Microfluidizer® high shear fluid processing systems to the Biotechnology and Pharmaceutical industries since 1984. As leader in the field, Microfluidics has enabled numerous companies and institutions to formulate, validate and produce licensed drugs for the worldwide healthcare market.
Companies seeking to produce difficult-to-formulate products or to find better methods of bio-processing can take advantage of complimentary sample testing at one of three Microfluidics facilities. Visit www.microfluidicscorp.com, email mixinginfo@mfics.com or contact Microfluidics at 800.370.5452 for application information.
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