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Antibody Array enables profiling of 725 proteins in 1 assay.

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April 3, 2007 - Panorama(TM) Antibody Microarray XPRESS Profiler725 promotes high-throughput multiplex protein expression profiling of serum, cell, or tissue extracts. Letting researchers screen expression changes in large numbers of proteins, its 725 specific antibodies are arrayed in duplicate on nitrocellulose slides compatible with DNA array scanners. Array antibodies detect human, mouse, and rat proteins associated with key cell signaling and gene regulation pathways.

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Original Press release

Sigma Aldrich Corp.
3050 Spruce St.
St. Louis, MO, 63103
USA



Sigma-Aldrich Launches Market-Leading Content Antibody Array that Enables Expression Profiling of 725 Proteins in a Single Assay


ST. LOUIS, March 15 -- Sigma-Aldrich (NASDAQ:SIAL), a leading $1.8 billion Life Science and High Technology company, is pleased to announce the launch of the Panorama(TM) Antibody Microarray XPRESS Profiler725 (http://sigma.com/expressionprofile), a high-throughput tool for multiplex protein expression profiling of serum, cell or tissue extracts.

"Researchers are increasingly seeking tools that can easily identify the more biologically-relevant changes that occur at the proteome level," said Dr. Richard Pembrey, Market Segment Manager, Functional Proteomics. "By combining the sensitivity of antibody detection with an increasing level of content, Panorama antibody microarray technology enables researchers to screen expression changes in large numbers of proteins in significantly less time than it would take using conventional protein detection methodology."

The Panorama XPRESS Profiler725 contains 725 highly specific antibodies, arrayed in duplicate on nitrocellulose slides compatible with the majority of DNA array scanners available today. The array antibodies detect human, mouse, and rat proteins associated with a variety of key cell signaling and gene regulation pathways. Targeted-content subsets of antibodies to Mitogen-Activated Protein Kinase (MAPK), Protein Kinase C (PKC) and p53 protein families are also represented on the array.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,500 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com/.

CONTACT: Sean Battles of Sigma-Aldrich, +1-314-286-7616, sean.battles@sial.com
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