December 8, 2006 - Based on asymmetrical Flow Field-Flow Fractionation, Eclipse system requires only one pump to generate all 3 required flow rates. Samples can be separated according to hydrodynamic radius in selected channel by interacting with cross-flow permeating through bottom wall. Developed for pharmaceutical industry, unit can characterize antibody preparations with respect to aggregation and identify impurities/contaminants at lower detection limit.

Related categories: Chemical Processing and Waste Management | Laboratory and Research Supplies and Equipment | Test and Measuring Instruments

Archive Press Release
(Products mentioned in this Archive Press Release may or may not be available from the manufacturer.)

Release date: November 1, 2006

Wyatt Technology's Eclipse(TM) Significantly Improves Resolution for Protein and Particle Separation

(1 November, 2006) - Wyatt Technology, the world leader in absolute macromolecular characterization instruments and software, introduces its Eclipse separation system. Designed for the analysis of protein, biopolymer and colloidal materials, the Eclipse system has been developed as an alternative to conventional column chromatography and is based on asymmetrical Flow Field-Flow Fractionation (AF4). Samples can be separated according to hydrodynamic radius in a selected channel. Wyatt Technology's new Eclipse channel technology significantly improves resolution whilst increasing peak height in the detector, without compromising resolution or peak shape.

The Eclipse is the only AF4 system that requires only one pump to generate all three flow rates that are required for the analysis. Additionally, the absence of pulsations is even more vital when the channel volume is reduced. Developed for the pharmaceutical industry, the Eclipse is able to characterize antibody preparations with respect to aggregation and allows for Impurities or contaminants, like aggregates, to be identified at a lower detection limit, as well as featuring a reduced dead volume.

Separation is achieved by interacting with a cross-flow permeating through the bottom wall, while the sample is transported by the longitudinal flow towards the channel outlet and the detectors. Endorsed by the Food and Drug Administration (FDA) as a necessary check of Size Exclusion Chromatography (SEC) analysis, there is no stationary phase which would result in the absorption or degradation, thereby enabling the separation of soluble molecules from colloidal constituents.

As well as enhanced resolution and peak height, consumption of eluent and analysis time is also reduced. The smaller channel is easier to handle for membrane replacement and has faster equilibration time, resulting in less down time and increased sample throughput.

Coupled with the new generation of Wyatt Technology's MALS detectors, the HELEOS and TREOS, characterization of proteins and biopolymers at nano-gram concentration range is feasible.

For more information on Wyatt Technology's new product innovations and services, please visit www.wyatt.com or e-mail info@wyatt.com

About Wyatt
Based in Santa Barbara, California, Wyatt Technology is the world's leading provider of instruments for absolute macromolecular characterization. With over 35 years' experience developing multi-angle light scattering detectors, working with customers in the biotechnology, chemical, petrochemical, pharmaceutical, academic and government arenas, Wyatt prides itself on its entrepreneurial spirit, and the uniqueness of its offerings. The Company's groundbreaking technology and uncompromising levels of customer care make Wyatt the global hallmark in its field. For more information, please visit www.wyatt.com

Company Information:
Name: Wyatt Technology Corp.
Address: 802 E. Cota St.
City: Santa Barbara
State: CA
ZIP: 93103
Country: USA
Phone: 805-963-5904
FAX: 805-965-4898
http://www.wyatt.com

Story Tools

Go Back |

E-Mail | Print | Post

	View Company Profile at ThomasNet.com
	Company web site
	More news from this company
	Search for suppliers of: Particle Size Analyzers Separators Laboratory Equipment & Supplies
	Join the forum discussion at: Tools of the Trade

Related Stories:
Oct 8, 2008	System automates protein and nanoparticle size measurement.
Sep 19, 2008	Process Control System meets laboratory requirements.
Sep 16, 2008	Pressure Reaction Vessel Kits prevent meltdown.
Sep 11, 2008	Ductless Fume Hoods come in 36 in. deep models.
Sep 9, 2008	Bioresearch Apparatus helps assess learning and memory.
Sep 3, 2008	Particle Size Analyzer automates sieve analysis process.
Aug 29, 2008	Sample Preparation Kit facilitates systems biology studies.
Aug 27, 2008	Low Pressure Mixing Pumps are compact and modular.
Aug 26, 2008	Laboratory Sterilizer does not use gases or open flames.
Aug 1, 2008	Modular Cooling System helps organize samples in labs.
Aug 1, 2008	NIR Spectrometer covers 850-2,500 nm wavelength range.
Jun 10, 2008	Anaerobic System achieves anaerobic conditions in 1-3 min.
May 2, 2008	Sink Strainer has built-in magnets to catch stirring bars.
Mar 12, 2008	Particle Characterization System features sample dispersion unit.
Mar 11, 2008	Polymerization Monitoring System offers real-time analysis.
Feb 29, 2008	Dry Block Heater features dual temperature control.
Feb 22, 2008	Bench Top Protector meets laboratory needs.
Feb 1, 2008	Turbomolecular Pump targets laboratory vacuum systems.
Jan 30, 2008	Glassware Washers come with single and/or double chamber.
Dec 26, 2007	Digital Lab Refractometer measures 11.5 x 8.5 x 3.0 in.

More New Product News from this company:
Oct 5, 2007	MALS Instrument facilitates macromolecular characterization.
Nov 16, 2006	Separation System is developed for pharmaceutical industry.
Jun 2, 2005	DLS System facilitates high-throughput screening.
Mar 29, 2005	Light Scattering Detector achieves dynamic range of 126 dB.

Other News from this company:
Oct 05, 2007	Wyatt Technology's New Calypso System Reduces Preparation Time and Noise Levels by Providing Continuous Flow to Detectors
Jul 31, 2007	Wyatt Technology's Dynapro Dynamic Light Scattering (DlS) Instrument Used in Innovative Study of Complex Assembly and Disassembly
May 10, 2007	Wyatt Technology Showcases Its Advanced Dynapro Titan Plate Reader at 234th ACS National Meeting & Exposition 2007
Nov 28, 2006	Wyatt Technology Europe's Eclipse Achieves Accurate and Reliable Characterisation of Micelles

Brought to you by Thomasnet.com Browse ThomasNet Directory

News provided by ThomasNet Industrial Newsroom^® (TIN). TIN is a comprehensive source of new and timely product information in the industrial marketplace. TIN supplies new product information to the web sites, e-marketplaces and print publications that serve the industrial marketplace. For press release submissions please go to http://news.thomasnet.com/submitpr.html. BY ACCESSING, BROWSING AND/OR USING THIS WEB SITE AND/OR ANY WEB SITES PROVIDED BY ProductNews.com, YOU AGREE TO BE BOUND BY THE TERMS OF USE AGREEMENT.