Light Scattering Detector analyzes pharmaceutical compounds.

Polymer Laboratories, Inc.    Amherst, MA 01002
May 12, 2006 Evaporative Light Scattering Detector, Model PL-ELS 2100, is available with optional Integrated Cooled Evaporator, Model PL-ELS 2100 Ice, which operates at temperatures down to 10°C to meet requirements for pharmaceutical analysis of non-UV absorbing, low molecular weight, semi-volatile analytes. Addition of evaporation gas not only allows low temperature operation with aqueous mobile phases, but also facilitates removal of water at sub-ambient temperatures.

SPE Device removes Palladium species from organic solutions.

Polymer Laboratories, Inc.    Amherst, MA 01002
Aug 10, 2005 PL-Thiol MP SPE removes Palladium (0) and (ll) species from variety of organic solvents. It can reduce solutions with palladium concentration of 1,000 ppm in water, THF, and DMF to less than 0.1 ppm after one pass under gravity drain. Polymeric SPE media is designed to be self-indicating when Palladium species are present, identifying when device is nearing capacity. Monodisperse macroporous polymeric SPE material can be used from pH 1–14.

GPC System performs polymer characterization and analysis.

Polymer Laboratories, Inc.    Amherst, MA 01002
Feb 01, 2005 Integrated PL-GPC 50 platform enables fully integrated triple detection with refractive index, viscometer, and light scattering detectors. Additional detector options for UV and ELSD are available, and combinations are supported with integrated software control and processing. Features provide network control for connection of proprietary instrumentation to obtain instant access for remote monitoring, control, and data collection.

Sample Preparation System suits range of polymer types.

Polymer Laboratories, Inc.    Amherst, MA 01002
Oct 01, 2004 Intended for manual dissolution and filtration of samples prior to GPC analysis, Model PL-SP 260VS combines controlled heating across temperature range of 30–260°C with gentle agitation and user-selectable speeds between 85–230 rpm. Pipettor device dispenses hot filtered sample solution from preparation vial directly into destination vials, with minimal handling. Choice of filtration media includes 1µm glass fiber and porous stainless steel.

Columns suit small-scale LC-MS and 2D chromatography.

Polymer Laboratories, Inc.    Amherst, MA 01002
Sep 27, 2004 Packed with reversed phase and both strong and weak cation and anion wide pore exchange media, Capillary and Micro Columns do not leach either soluble or particulate species. Capillary columns, with internal diameter of 300 µm, are suited for pg to ng sample sizes and are used with flow rates around 4 µl/min. With internal diameter of 1.0 mm, Micro Columns are suited for ng to mg samples sizes and typically operate at flow rates of 40 µl/min.

GPC/SEC Columns provide analysis in less than 10 min.

Polymer Laboratories, Inc.    Amherst, MA 01002
Sep 20, 2004 Suited for analysis of organic and water soluble polymers, PL Rapide Series includes 100 x 10 mm columns, which cover complete spectrum of molecular weight and can be used at flow rates as high as 3.0 mL/min. Typical applications include high-throughput screening from combinatorial synthesis experiments and rapid process monitoring where trends are more important than high resolution and precise analyses.

GPC Columns provide environmental sample clean-up.

Polymer Laboratories, Inc.    Amherst, MA 01002
Sep 03, 2004 PL EnviroPrep GPC Columns permit one-stage clean-up procedure, according to EPA Methods, for determination of pesticides in variety of matrices such as soil and animal tissue. Matrix is extracted and higher molecular weight fractions such as lipids, polymers, natural resins, and dispersed high molecular weight components are eliminated. Featuring 10 µm particle size and 100Ã… pore size, columns are useful for looking at low levels of pollutants.

High Resolution Columns are designed for organic GPC.

Polymer Laboratories, Inc.    Amherst, MA 01002
Jul 07, 2004 PlusPore series columns, designed for high resolution organic gel permeation chromatography (GPC), are made using polymerization process to produce particles which exhibit specific, controlled pore structure. Multi-pore structures have pore volume compared to PS/DVB packing materials and offer chemical and physical stability. They permit transfer across full range of organic solvents with little change in shape of calibration curve or efficiency of columns.

ELSD System has nitorgen generator with no moving parts.

Polymer Laboratories, Inc.    Amherst, MA 01002
Jun 08, 2004 Evaporative Light Scattering Detector (ELSD) PL-ELS 2100 incorporates Parker Balston Model N2-4000 nitrogen generator for delivery of 99% pure nitrogen to system. Instrument handles low-temperature HPLC applications with semi-volatile compounds, and carrier gas is nitrogen. System requires pressure of 60–100 psi at flow rates up to 3.25 l/min. Nitrogen generator has no moving parts and requires no electricity.

Interface offers polymer characterization capabilities.

Polymer Laboratories, Inc.    Amherst, MA 01002
Oct 13, 2003 GPC-FTIR interface couples gel permeation chromatography (GPC)with fourier transform infra-red spectroscopy (FTIR) in continuous flow mode. Flow cell, which slots directly onto optical bench of spectrometer, minimizes band broadening and is available with choice of window materials. Cell assembly can operate at ambient temperature or be controlled up to 175°C. Interface is compatible with any GPC system and most industry standard FTIR spectrometers.

Polymer-Standards Kit facilitates column calibration.

Polymer Laboratories, Inc.    Amherst, MA 01002
Feb 01, 2003 EasiVial kit consists of three 4 ml vials, each containing mixture of 4 pre-weighed polymer standards. Each kit contains 30 color-coded vials and characterization data for each supplied polymer. Molecular weights of polymer standards achieve baseline resolution when used with column configurations and multi-detector GPC systems. User adds solvent to vial, awaits dissolution, and can generate 12-point GPC calibration with 3 injections.

Software provides GPC and multi-detection capabilities.

Polymer Laboratories, Inc.    Amherst, MA 01002
Feb 01, 2003 Cirrusâ„¢ v2.0 includes Data Reviewer modules for post-analysis reviewing and reporting of chromatograms and calculated results. It graphically reviews set of sample chromatograms and molecular-weight distribution plots. Result summaries for set of sample analyses can be generated with direct data transfer to third party software. Cirrus includes normalization routines, reporting options, and optional, automatic data filtering.

Column separates peptides and proteins.

Polymer Laboratories, Inc.    Amherst, MA 01002
Feb 01, 2003 Model PLRP-S 3 µm column comes in 100Ã… and 300Ã… pore sizes. Media is offered packed in short columns for rapid resolution LC/MS, where complete chromatographic resolution is not required, as MS is used to provide detailed information. Longer columns in 2.1 and 1.0 mm ID are available for higher resolution separations. PLRP-S 100Ã… 3µm is suitable for peptide separations, while larger pore size PLRP-S 300Ã… 3 µm is recommended for protein analysis.

Sample Dilution/Injection System suits GPC chromatography.

Polymer Laboratories, Inc.    Amherst, MA 01002
Feb 01, 2003 Suited for Gel Permeation Chromatography (GPC), PL XT-R is based on robotic platform and integrates sample preparation and autosampling functions. Product supports all GPC chromatographs operating in temperature range from 30-220°C. Up to 96 sample-filled vials are accommodated in blocks in X-Y array. Solvent-filled vials are subjected to controlled heating and magnetic stirring. System includes robotic arm dispenser, heated injection valve, and heated transfer line.

Multi Detector Software allows interactive calculations.

Polymer Laboratories, Inc.    Amherst, MA 01002
Jan 28, 2002 Cirrus(TM) provides polymer characterization by multi detector GPC, and is used to acquire and analyze data from GPC systems fitted with any combination of refractive index, light scattering and viscosity detectors. Cirrus incorporates 24 bit, high resolution, low noise data acquisition system, PL DataStream, to interface with up to 4 user-selectable detector outputs. Software derives branching parameters from either Mark Houwink or conformation plots.

Light Scattering Detector is for micro and capillary HPLC.

Polymer Laboratories, Inc.    Amherst, MA 01002
Jan 21, 2002 PL-ELS 1000µ microbore evaporative light scattering detector provides baseline stability for HPLC separations requiring gradient elution. Detector operates with eluent flow rates from 1 to 500 µl/min, detects all non-volatile solutes, and does not require UV chromophore. It can be used as standalone detector for separations using capillaries down to 300 µm ID, or can be used as split flow concentration detector in conjunction with LC-MS systems.