Malvern Showcases New Systems for Foreign Particle Determination, Protein Characterization and Rheology Measurement
2008 American Association of Pharmaceutical Scientists Annual Meeting & Exposition
Booth # 1348
5 November 2008: Malvern, UK: Malvern Instruments will demonstrate a new application for foreign particle determination on filters, and will show new systems for protein characterization and rheology measurement at the 2008 AAPS Annual Meeting & Exposition (17-20 Nov, Atlanta, USA). Foreign particulate matter determination on the Morphologi G3, the Zetasizer APS and Zetasizer µV systems for protein characterization in pharmaceutical and biotechnology applications, and the radical new Kinexus rheometer platform have all been launched since the beginning of September. This is one of the first events at which they are being exhibited.
As well as supporting the exhibition, Malvern is participating in the conference. Dr Paul Kippax, product manager for laser diffraction systems at Malvern, will contribute a paper on 'Method Development and Validation for Particle Size Measurements'. His presentation will examine requirements for the development and validation of particle sizing methods, with reference the FDA's guidance documentation, the US pharmacopoeia and the available international standards.
Morphologi G3 : Foreign particulate matter - detection, enumeration, size classification
A new capability on Malvern's award-winning Morphologi G3 automated particle characterization system enables the fully automated detection, enumeration and size classification of foreign particulate matter (FPM) collected on a filter. In the pharmaceutical industry this is especially important in controlling particulate contamination of materials for injection or inhalation. Analysis of FPM on filters has traditionally been the preserve of manual light microscopy. Now, the Morphologi G3 brings fully automated image analysis to accelerate characterization and remove any operator subjectivity.
http://www.malvern.com/LabEng/products/morphologi/contamination_monitoring.htm
Zetasizer APS: Protein characterization in microplates
The Zetasizer APS is a new dynamic light scattering (DLS) system which automates size measurements of samples in 96- or 384-well microplates. Designed primarily for protein specialists, it is fully automated, simply requiring users to insert the plate and press start. The Zetasizer APS allows quick and easy investigation of a protein's condition at different stages of the purification process, and at later stages of formulation under a range of environmental conditions. The measurement technology used delivers results with exactly the same high precision and reproducibility you would expect from a research grade batch DLS system. www.malvern.com/zetasizerAPS
Zetasizer µV: Requires just 2 microlitres for biomolecule characterization
The new Zetasizer µV is an advanced light scattering system specifically intended for the characterization of proteins and other biomolecules. Designed and optimized for maximum sensitivity and minimum sample volume, the Zetasizer µV is a dedicated system that supports improved understanding and management of a wide range of biomolecule applications, including: optimizing sample and storage conditions; verifying the quaternary structure of protein complexes; identifying thermal characteristics; and assessing protein solubility and sample purity. www.malvern.com/zetasizerMicroV
The new Kinexus - more rheology, less effort
Kinexus is the radical new rotational rheometer platform from Malvern Instruments. Completely redefining the rheometer, Kinexus enables users to spend less time learning how to interact with their system and more time investigating ways to characterize and enhance a material's performance. Embedding expert knowledge and adaptive intelligence within the instrument delivers application-relevant and high quality data for all users, generating information that will truly add value to a product or process. www.malvern.com/kinexus
About Malvern Instruments
Malvern Instruments provides a range of complementary materials characterization tools that deliver inter-related measurements reflecting the complexities of particulates and disperse systems, nanomaterials and macromolecules. Analytical instruments from Malvern are used in the characterization of a wide variety of materials, from industrial bulk powders to the latest nanomaterials and delicate macromolecules. A broad portfolio of innovative technologies is combined with intelligent, user-friendly software. These systems deliver industrially relevant data enabling our customers to make the connection between micro (such as particle size) and macro (bulk) material properties (rheology) and chemical composition (chemical imaging).
Particle size distribution, particle shape information, zeta potential, molecular weight, chemical composition, and bulk materials properties can all be determined with instruments from the Malvern range. The company's laboratory, at-line, on-line and in-line solutions are proven in sectors as diverse as cement production and pharmaceutical drug discovery.
Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Korea and Japan, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com
For press information, please contact:
Trish Appleton, Kapler Communications
Knowledge Centre, Wyboston Lakes, Great North Road,
Wyboston, Bedfordshire, MK44 3BY, UK
Tel: +44 (0)1480 479280;
Fax: +44 (0)1480 470343
trish@kapleronline.com
USA contact:
Marisa Fraser, Malvern Instruments Inc.
117 Flanders Road, Westborough, MA 01581-1042 USA
Tel: +1 508 768 6400
Fax: +1 508 768 6403
marisa.fraser@malvern.com
Please send sales enquiries to:
Alison Vines, Malvern Instruments Ltd
Enigma Business Park, Grovewood Road, Malvern, Worcestershire WR14 1XZ UK
Tel: +44 (0) 1684 892456;
Fax: +44 (0) 1684 892789
salesinfo@malvern.com
